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Clinical trials and research at Philogen S.p.A.

• 9Clinical trials
• 6Countries

Newest trials

All recruiting trials (9)

• F8IL10 injections directly into a swollen joint for rheumatoid arthritis

  This trial tests whether injecting F8IL10 into a single swollen joint is safe and what dose adults with rheumatoid arthritis can tolerate.

  Recruiting Phase 1 Philogen S.p.A. · Reggio Emilia, Reggio Emilia and 1 other locations · NCT07245992

• L19IL2/L19TNF therapy for locally advanced cutaneous squamous cell carcinoma

  This study tests a combination treatment injected directly into skin tumors to see if it helps people whose locally advanced cutaneous squamous cell carcinoma progressed after or couldn’t tolerate prior immune therapy.

  Recruiting at 17 sites Phase 2 Philogen S.p.A. · Orange, California and 18 other locations · NCT07228442

• L19IL2/L19TNF in Locally Advanced Basal Cell Carcinoma

  This trial tests whether injecting L19IL2/L19TNF directly into injectable skin lesions can help patients with locally advanced basal cell carcinoma who have progressed on or cannot tolerate other treatments.

  Recruiting at 15 sites Phase 2 Philogen S.p.A. · Tampa, Florida and 17 other locations · NCT07227870

• L19IL2, L19TNF, or both for locally advanced basal cell carcinoma

  This study tests whether injecting L19IL2, L19TNF, or the combination into skin tumors helps people with locally advanced basal cell carcinoma who can’t have surgery or radiation.

  Recruiting at 15 sites Phase 2 Philogen S.p.A. · Tampa, Florida and 17 other locations · NCT07227350

• Testing [177Lu]Lu-OncoFAP-23 alone or with L19-IL2 for metastatic FAP-positive solid tumors

  This study will test whether the radioligand [177Lu]Lu-OncoFAP-23, given alone or together with the antibody-cytokine L19-IL2, is safe and shows early benefit in adults with advanced or metastatic FAP-positive solid tumors.

  Recruiting at 2 sites Phase 1 Philogen S.p.A. · Bergamo, Bergamo and 3 other locations · NCT06640413

• Evaluating new treatments for advanced melanoma with pembrolizumab

  This study is testing new treatment combinations for patients with advanced melanoma who haven't responded to previous therapies to see if they can improve their chances of survival.

  Recruiting at 5 sites Phase 2 Philogen S.p.A. · Hartford, Connecticut and 6 other locations · NCT06284590

• Evaluating the safety and early effectiveness of IL12-L19L19 in advanced solid tumors

  This study is testing a new treatment called IL12-L19L19 to see if it's safe and effective for people with advanced solid tumors who have already tried other immune therapies.

  Recruiting at 9 sites Phase 1 Philogen S.p.A. · Hamburg, Free and Hanseatic City of Hamburg and 10 other locations · NCT04471987

• Exploring a new treatment for newly diagnosed glioblastoma

  This study is testing a new treatment that combines L19TNF with standard chemotherapy for people who have just been diagnosed with glioblastoma to see if it works better than the usual treatment alone.

  Recruiting Phase 1/2 Philogen S.p.A. · Zurich · NCT04443010

• Daromun treatment for advanced melanoma before surgery

  This study is testing if a new treatment called Daromun can help people with advanced melanoma live longer without their cancer coming back after surgery.

  Recruiting at 26 sites Phase 3 Philogen S.p.A. · Phoenix, Arizona and 36 other locations · NCT03567889

Quick answers

How many clinical trials run by Philogen S.p.A. are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in Italy (7 trials), Germany (5 trials), United States (5 trials), Spain (4 trials), Switzerland (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1: 3, Phase 1/2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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