Sponsor or institution

Clinical trials and research at Penumbra Inc.

• 4Clinical trials
• 15Countries

Newest trials

All recruiting trials (4)

• FORWARD: Functional Outcomes in Real-World Treatment and Revascularization of Non-dominant and Distal M2 Occlusions

  This study tests how the Penumbra System works in real-world patients with non-dominant or distal M2 occlusions who have an acute ischemic stroke, comparing endovascular thrombectomy to medical management alone.

  Recruiting at 7 sites Penumbra Inc. · Englewood, Colorado and 6 other locations · NCT07749170

• Real-world performance and safety of the Penumbra System in acute ischemic stroke

  This project will test how the Penumbra mechanical thrombectomy system performs and how safe it is in adults aged 18–75 who have acute ischemic stroke and are eligible for clot removal.

  Recruiting at 12 sites Penumbra Inc. · Nedlands, Western Australia and 11 other locations · NCT07107022

• Removing leg artery clots with the Indigo Aspiration System for acute lower‑limb ischemia

  This will test whether the Indigo Aspiration System can safely remove clots and restore blood flow in adults with recent (≤14 days) lower‑limb acute ischemia.

  Recruiting at 44 sites Penumbra Inc. · Scottsdale, Arizona and 44 other locations · NCT06747117

• Evaluating the long-term safety and outcomes of the Indigo Aspiration System for pulmonary embolism treatment

  This study is testing how safe and effective the Indigo Aspiration System is for treating pulmonary embolism in patients over the long term.

  Recruiting at 74 sites Penumbra Inc. · Long Beach, California and 78 other locations · NCT04798261

Quick answers

How many clinical trials run by Penumbra Inc. are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 15 countries. The most sites are in United States (3 trials), Australia (3 trials), Germany (3 trials), Switzerland (3 trials), Brazil (2 trials). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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