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Clinical trials and research at Palvella Therapeutics, INC.

• 2Clinical trials
• 3NIH research projects
• 1Country

All recruiting trials (2)

• PTX-022 (sirolimus) 3.9% topical gel for angiokeratomas.

  This trial will test whether PTX-022, a 3.9% sirolimus topical gel, is safe and helps people aged 6 and older who have angiokeratomas.

  Recruiting at 2 sites Phase 2 Palvella Therapeutics, Inc. · Sherman Oaks, California and 3 other locations · NCT07552077

• Evaluating a gel treatment for adults with Pachyonychia Congenita

  This study is testing a new gel treatment for adults with Pachyonychia Congenita to see how safe it is and how it works in the body over time.

  Recruiting Phase 3 Palvella Therapeutics, Inc. · New Brighton, Minnesota · NCT05643872

NIH-funded research (3)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• PTX-022 ointment gel for rare microcystic lymphatic malformations (LM)

  A new topical gel (PTX-022) is being tested to help people with a rare, lifelong skin and lymphatic condition called microcystic LM.

  NIH research Palvella Therapeutics, INC. · Wayne, United States · NIH-11403007

• Topical sirolimus (PTX-022) for microcystic lymphatic malformations

  This project offers a topical sirolimus gel (PTX-022) for people with microcystic lymphatic malformations to try to reduce leaking, infections, and other skin symptoms while checking safety.

  NIH research Palvella Therapeutics, INC. · Wayne, United States · NIH-11196066

• Evaluating a new treatment for microcystic lymphatic malformations

  This study is testing a new gel called PTX-022 to see if it can safely help people with microcystic lymphatic malformations, a rare condition that affects the lymphatic system, and it's looking for participants to see how well it works and if there are any side effects.

  NIH research Palvella Therapeutics, INC. · Wayne, United States · NIH-11104574

Quick answers

How many clinical trials run by Palvella Therapeutics, INC. are recruiting right now?

2, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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