Sponsor or institution

Clinical trials and research at National Marrow Donor Program

• 7NIH research projects

NIH-funded research (7)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Optimizing busulfan dosing for infants with SCID undergoing stem cell transplant

  This grant tests the safest busulfan dosing levels in infants with SCID to help achieve good T and B cell recovery after a stem cell transplant.

  NIH research National Marrow Donor Program · Minneapolis, United States · NIH-11555650

• Providing Pediatric Transplant Access and Personalized Conditioning for Children

  A national program helps kids with life-threatening blood diseases access allogeneic hematopoietic cell transplantation and tailors pre-transplant chemotherapy to each child.

  NIH research National Marrow Donor Program · Minneapolis, United States · NIH-11392701

• Optimizing busulfan dosing for infants with SCID undergoing donor stem cell transplant

  A study tests different busulfan doses in babies with SCID to see which helps transplant success and immune recovery.

  NIH research National Marrow Donor Program · Minneapolis, United States · NIH-11392252

• Choosing the right busulfan dose before transplant for infants with IL2RG, JAK3, or RAG1/2 SCID

  This project compares two chemotherapy (busulfan) dosing strategies to help infants with certain genetic forms of SCID regain their immune cells after a stem cell transplant.

  NIH research National Marrow Donor Program · Minneapolis, United States · NIH-11378897

• Expanding access to bone marrow and cellular therapies for children with life‑threatening diseases

  This program helps children with serious blood and genetic conditions get personalized bone marrow and cellular therapies through a network of transplant centers and trials.

  NIH research National Marrow Donor Program · Minneapolis, United States · NIH-11170039

• Finding the best busulfan dose for infants with SCID

  This project compares lower versus moderate doses of the chemotherapy drug busulfan to help infants with IL2RG-, JAK3-, or RAG1/2-related SCID rebuild their immune systems after a donor bone marrow transplant.

  NIH research National Marrow Donor Program · Minneapolis, United States · NIH-11168867

• Access to clinical trials for children with life-threatening diseases through transplantation.

  This study is all about making bone marrow transplants better for kids with blood diseases by using DNA tests to personalize their treatment and find the right chemotherapy dose just for them.

  NIH research National Marrow Donor Program · Minneapolis, United States · NIH-10939222

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