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Clinical trials and research at Major Extremity Trauma Research Consortium

• 5Clinical trials
• 1Country

Newest trials

All recruiting trials (5)

• Using negative pressure therapy to improve healing in high-risk fractures

  This study is testing if a special type of wound therapy can help people with high-risk tibial fractures heal better and avoid infections compared to regular bandages.

  Recruiting at 6 sites Phase 3 Major Extremity Trauma Research Consortium · Baltimore, Maryland and 5 other locations · NCT06337292

• Tissue ultrafiltration to prevent acute compartment syndrome after severe tibia fractures

  This trial tests whether placing tissue ultrafiltration (TUF) catheters in adults 18–60 with severe proximal tibia or tibial shaft fractures can lower muscle pressure and prevent acute compartment syndrome compared with standard care.

  Recruiting at 4 sites Major Extremity Trauma Research Consortium · Baltimore, Maryland and 3 other locations · NCT05889559

• Comparing oral and intravenous antibiotics for treating infected nonunion of fractures

  This study is testing whether taking antibiotics by mouth works as well as getting them through an IV for people with infected fractures that haven't healed properly after surgery.

  Recruiting at 9 sites Phase 3 Major Extremity Trauma Research Consortium · Indianapolis, Indiana and 12 other locations · NCT05699174

• Evaluating fibroblast injections for amputees

  This study is testing if injections made from patients' own skin cells can help improve the healing and comfort of adults with lower leg amputations using prostheses.

  Recruiting Phase 2 Major Extremity Trauma Research Consortium · Baltimore, Maryland · NCT04839497

• New antibiotic care strategy for severe open fractures

  This study is testing a new antibiotic treatment plan for people with severe open fractures in their legs and ankles to see if it helps reduce infections and improve healing compared to the usual care.

  Recruiting at 31 sites Phase 3 Major Extremity Trauma Research Consortium · Redwood City, California and 30 other locations · NCT04678154

Quick answers

How many clinical trials run by Major Extremity Trauma Research Consortium are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 3, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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