Sponsor or institution

Clinical trials and research at Madrigal Pharmaceuticals, Inc.

• 5Clinical trials
• 2Countries

Newest trials

All recruiting trials (5)

• Rezdiffra with diabetes and pioglitazone or dapagliflozin in adults with MASH and F2-F3 fibrosis

  This study tests whether Rezdiffra (resmetirom) can be safely used together with common diabetes medicines in adults with MASH and moderate to advanced liver fibrosis.

  Recruiting at 3 sites Phase 4 Madrigal Pharmaceuticals, Inc. · Chandler, Arizona and 15 other locations · NCT07848191

• Resmetirom for MASH with HFpEF in adults

  This study tests whether resmetirom can be given safely and show liver-related effects in adults with MASH and heart failure with preserved ejection fraction over 24 weeks.

  Recruiting at 5 sites Phase 1 Madrigal Pharmaceuticals, Inc. · Peoria, Arizona and 4 other locations · NCT07830758

• Resmetirom in children and teens with MASH

  This study tests how safe resmetirom is and how it acts in the body of kids aged 6 to 17 who have MASH with liver fibrosis.

  Recruiting Phase 2 Madrigal Pharmaceuticals, Inc. · Indianapolis, Indiana · NCT07763015

• Rezdiffra pregnancy and breastfeeding registry for women with NASH

  This registry collects information about pregnancy and infant health for women with NASH who were exposed to Rezdiffra during pregnancy or while breastfeeding.

  Recruiting Madrigal Pharmaceuticals, Inc. · West Conshohocken, Pennsylvania · NCT07541469

• Resmetirom for post-liver transplant MASH with moderate to advanced fibrosis

  This trial will test resmetirom versus placebo to see if it reduces liver fat and improves fibrosis in people who developed MASH after a liver transplant.

  Recruiting at 12 sites Phase 2 Madrigal Pharmaceuticals, Inc. · La Jolla, California and 16 other locations · NCT07335601

Quick answers

How many clinical trials run by Madrigal Pharmaceuticals, Inc. are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (5 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 4: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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