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Clinical trials and research at Karuna Therapeutics, Inc., a Bristol Myers Squibb company

• 8Clinical trials
• 33Countries

Newest trials

All recruiting trials (8)

• Relapse prevention with KarXT in schizophrenia

  This test checks if KarXT can help prevent relapse in people living with schizophrenia who’ve recently been hospitalized and still have noticeable symptoms.

  Recruiting at 11 sites Phase 3 Karuna Therapeutics, Inc., a Bristol Myers Squibb company · Bentonville, Arkansas and 53 other locations · NCT07686263

• KarXT with antiemetics safety in healthy volunteers

  This study tests whether adding anti-nausea medicine to KarXT helps prevent nausea and vomiting in healthy volunteers.

  Recruiting at 4 sites Phase 4 Karuna Therapeutics, Inc., a Bristol Myers Squibb company · Los Alamitos, California and 3 other locations · NCT07681076

• Long-term safety of KarXT and KarX-EC in adolescents with schizophrenia or autism-related irritability

  This trial will test whether taking KarXT (for schizophrenia) or KarX-EC (for autism-related irritability) is safe and tolerable for adolescents over the long term.

  Recruiting at 21 sites Phase 3 Karuna Therapeutics, Inc., a Bristol Myers Squibb company · Dothan, Alabama and 104 other locations · NCT07424404

• How CYP2D6 genetic differences change xanomeline levels after taking KarXT in healthy adults

  This test will see if genetic differences in CYP2D6 change the amount of xanomeline in the blood after healthy adults take KarXT.

  Recruiting Phase 1 Karuna Therapeutics, Inc., a Bristol Myers Squibb company · Anaheim, California and 2 other locations · NCT07204418

• Evaluating KarXT for treating psychosis in Alzheimer's patients

  This study is testing a new treatment called KarXT to see if it can help older adults with Alzheimer's who are experiencing severe psychosis.

  Recruiting at 162 sites Phase 3 Karuna Therapeutics, Inc., a Bristol Myers Squibb company · Chandler, Arizona and 295 other locations · NCT06585787

• KarXT for psychosis in people with Alzheimer's disease

  This Phase 3 test will see if KarXT reduces hallucinations and delusions in people aged 55–90 who have Alzheimer's-related psychosis.

  Recruiting at 7 sites Phase 3 Karuna Therapeutics, Inc., a Bristol Myers Squibb company · Chandler, Arizona and 156 other locations · NCT06126224

• Long-term safety assessment of KarXT for Alzheimer's-related psychosis

  This study is testing the long-term safety of a treatment called KarXT for people with Alzheimer's-related psychosis who have already participated in earlier trials.

  Recruiting at 132 sites Phase 3 Karuna Therapeutics, Inc., a Bristol Myers Squibb company · Homewood, Alabama and 431 other locations · NCT05980949

• Evaluating KarXT for treating psychosis in Alzheimer's patients

  This study is testing a new treatment called KarXT to see if it can help people with Alzheimer's who are experiencing psychosis and prevent them from getting worse.

  Recruiting at 36 sites Phase 3 Karuna Therapeutics, Inc., a Bristol Myers Squibb company · Homewood, Alabama and 128 other locations · NCT05511363

Quick answers

How many clinical trials run by Karuna Therapeutics, Inc., a Bristol Myers Squibb company are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 33 countries. The most sites are in United States (8 trials), Poland (5 trials), Spain (5 trials), Bulgaria (4 trials), France (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 6, Phase 1: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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