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Clinical trials and research at Jazz Pharmaceuticals

• 15Clinical trials
• 35Countries

Newest trials

All recruiting trials (15)

• JZP269 safety and PK/PD in healthy adults

  This study tests JZP269, an orexin-2 receptor activator, to see if it is safe and how it behaves in the body of healthy adults.

  Recruiting Phase 1 Jazz Pharmaceuticals · Lincoln, Nebraska and 1 other locations · NCT07813663

• JZP926 capsule for Juvenile Myoclonic Epilepsy: safety and seizure reduction in youths

  We’re testing if JZP926 capsule added to usual treatment can reduce myoclonic seizure days in people 10 and older with juvenile myoclonic epilepsy, compared with a placebo.

  Recruiting at 3 sites Phase 2/3 Jazz Pharmaceuticals · Phoenix, Arizona and 22 other locations · NCT07723963

• Expanded-dosing Xywav vs placebo in narcolepsy and IH

  This study tests whether expanded nightly dosing of Xywav helps adults with narcolepsy or idiopathic hypersomnia, compared with placebo.

  Recruiting at 15 sites Phase 3 Jazz Pharmaceuticals · Birmingham, Alabama and 14 other locations · NCT07625280

• JZP3507 (ONC206) for recurrent Grade 2/3 meningioma

  A pill-based therapy (JZP3507) is being tested to see if it can help adults with recurrent grade 2 or 3 meningioma who have not benefited from standard treatments.

  Recruiting at 6 sites Phase 2 Jazz Pharmaceuticals · San Francisco, California and 7 other locations · NCT07533942

• Lurbinectedin plus durvalumab for extensive-stage small-cell lung cancer after initial treatment

  This study tests whether adding durvalumab to lurbinectedin as maintenance after initial therapy helps people whose ES-SCLC has not progressed.

  Recruiting at 6 sites Phase 2 Jazz Pharmaceuticals · Los Angeles, California and 5 other locations · NCT07459634

• ONC206 (JZP3507) for advanced pheochromocytoma and paraganglioma

  This trial will test the oral drug ONC206 in adults with unresectable or treatment‑refractory pheochromocytoma or paraganglioma to see if it shrinks tumors or controls disease.

  Recruiting at 9 sites Phase 2 Jazz Pharmaceuticals · Los Angeles, California and 8 other locations · NCT07282587

• Cannabidiol oral solution for treating focal-onset seizures

  We will test whether a cannabidiol oral solution (CBD-OS) can reduce focal-onset seizures in people aged 12 to 75 who are taking 1–4 stable antiseizure medications.

  Recruiting at 21 sites Phase 1 Jazz Pharmaceuticals · Phoenix, Arizona and 23 other locations · NCT07233239

• Neoadjuvant zanidatamab plus chemotherapy for HER2-positive early breast cancer

  This study will test if adding zanidatamab to chemotherapy given before surgery helps people with HER2-positive early-stage breast cancer.

  Recruiting at 53 sites Phase 2 Jazz Pharmaceuticals · Long Beach, California and 52 other locations · NCT07102381

• Evaluating zanidatamab for HER2-expressing tumors

  This study is testing a new drug called zanidatamab to see if it can help people with certain types of cancer that have high levels of HER2 and who have already tried other treatments without success.

  Recruiting at 30 sites Phase 2 Jazz Pharmaceuticals · Prescott, Arizona and 41 other locations · NCT06695845

• Comparing zanidatamab and trastuzumab for metastatic HER2-positive breast cancer treatment

  This study is testing whether a new treatment called zanidatamab, used with chemotherapy, works better than the standard treatment trastuzumab with chemotherapy for people with advanced HER2-positive breast cancer who haven't responded well to previous therapies.

  Recruiting at 163 sites Phase 3 Jazz Pharmaceuticals · Phoenix, Arizona and 165 other locations · NCT06435429

• Zanidatamab combined with standard therapy for advanced HER2-positive biliary tract cancer

  This study is testing if a new treatment combining Zanidatamab with standard chemotherapy can help people with advanced HER2-positive biliary tract cancer feel better and live longer.

  Recruiting at 69 sites Phase 3 Jazz Pharmaceuticals · Duarte, California and 184 other locations · NCT06282575

• Monitoring pregnancy outcomes for patients using Epidiolex during pregnancy

  This study looks at how using Epidiolex during pregnancy affects the health of mothers and their babies to see what outcomes they experience.

  Recruiting at 3 sites Jazz Pharmaceuticals · Morgantown, West Virginia and 2 other locations · NCT06113237

• JZP898 infusion for advanced metastatic solid tumors

  This study is testing a new treatment called JZP898, alone and with another drug, to see if it can help adults with advanced solid tumors feel better and improve their health.

  Recruiting at 10 sites Phase 1 Jazz Pharmaceuticals · Encinitas, California and 9 other locations · NCT06108050

• Lurbinectedin treatment for young patients with relapsed Ewing sarcoma

  This study is testing if a new drug called lurbinectedin can safely help young patients with relapsed Ewing sarcoma feel better and improve their treatment options.

  Recruiting at 16 sites Phase 1/2 Jazz Pharmaceuticals · Los Angeles, California and 15 other locations · NCT05734066

• Treatment with ONC201 for patients with H3 K27M-mutant diffuse glioma after radiotherapy

  This study is testing if the drug ONC201 can help people with a specific type of brain tumor live longer and stay healthier after they finish their initial radiation treatment.

  Recruiting at 94 sites Phase 3 Jazz Pharmaceuticals · Phoenix, Arizona and 161 other locations · NCT05580562

Quick answers

How many clinical trials run by Jazz Pharmaceuticals are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 35 countries. The most sites are in United States (15 trials), Germany (5 trials), Italy (5 trials), Spain (5 trials), Canada (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 5, Phase 3: 4, Phase 1: 3, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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