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Clinical trials and research at Hoosier Cancer Research Network

• 18Clinical trials
• 1Country

Newest trials

All recruiting trials (18)

• Selinexor with Carfilzomib, Isatuximab and Dexamethasone for relapsed or refractory multiple myeloma

  This trial tests whether a four-drug combination can help adults with relapsed or refractory multiple myeloma when they've had at least one prior treatment.

  Recruiting Phase 1/2 Hoosier Cancer Research Network · Madison, Wisconsin · NCT07479979

• Olutasidenib after venetoclax in IDH1-mutated relapsed/refractory AML

  This study tests whether olutasidenib can help adults with IDH1-mutated AML that has relapsed or not responded to venetoclax-based therapy.

  Recruiting Phase 2 Hoosier Cancer Research Network · Winston-Salem, North Carolina · NCT07471841

• Zanzalintinib for aggressive variant prostate cancer

  This phase 2 study tests whether taking zanzalintinib once daily can help men with aggressive variant prostate cancer.

  Recruiting Phase 2 Hoosier Cancer Research Network · Milwaukee, Wisconsin · NCT07218666

• First-line immune-checkpoint antibody combinations for advanced clear cell kidney cancer

  This trial tests whether combining fianlimab and cemiplimab, with or without ipilimumab, works better than the standard ipilimumab plus nivolumab as first treatment for people with advanced clear cell kidney cancer.

  Recruiting at 5 sites Phase 2 Hoosier Cancer Research Network · Washington D.C., District of Columbia and 4 other locations · NCT07188896

• Combination of XL092 and Immunotherapy for Advanced Clear Cell Kidney Cancer

  This study is testing if a new drug called XL092, alone or with another treatment called nivolumab, can help people with advanced clear cell kidney cancer who haven't responded well to previous therapies.

  Recruiting at 5 sites Phase 2 Hoosier Cancer Research Network · La Jolla, California and 4 other locations · NCT06863311

• Treatment for advanced small bowel tumors using NALIRIFOX

  This study tests a new combination treatment called NALIRIFOX to see if it can help people with advanced small bowel tumors feel better and manage their disease.

  Recruiting at 7 sites Phase 2 Hoosier Cancer Research Network · Tampa, Florida and 6 other locations · NCT06835387

• Combination treatment for muscle-invasive bladder cancer

  This study is testing a new combination of two medications to see if they can help people with muscle-invasive bladder cancer avoid surgery and improve their treatment outcomes.

  Recruiting at 5 sites Phase 2 Hoosier Cancer Research Network · Duarte, California and 4 other locations · NCT06809140

• Zanzalintinib plus nivolumab before surgery for advanced clear cell kidney cancer

  This will try daily oral zanzalintinib together with regular nivolumab infusions for 12 weeks in adults with locally advanced or inoperable clear cell kidney cancer to shrink tumors and see if surgery becomes possible.

  Recruiting at 3 sites Phase 2 Hoosier Cancer Research Network · St Louis, Missouri and 3 other locations · NCT06794229

• Pemigatinib plus durvalumab for previously treated advanced intrahepatic cholangiocarcinoma with FGFR2 fusion

  This will test whether combining the FGFR inhibitor pemigatinib with the immunotherapy durvalumab helps adults with advanced intrahepatic cholangiocarcinoma that has an FGFR2 fusion and who have already received prior treatment.

  Recruiting at 3 sites Phase 2 Hoosier Cancer Research Network · Birmingham, Alabama and 2 other locations · NCT06728410

• Combining Durvalumab and Monalizumab for Bladder Cancer Treatment

  This study is testing a combination of two drugs, durvalumab and monalizumab, to see if they can help people with certain types of bladder cancer that haven't responded to standard treatment.

  Recruiting at 5 sites Phase 2 Hoosier Cancer Research Network · San Francisco, California and 4 other locations · NCT06503614

• Treatment for early-stage anal cancer using pembrolizumab and chemotherapy

  This study is testing a new combination of pembrolizumab, chemotherapy, and radiation to see if it can effectively treat early-stage anal cancer in patients who haven't received treatment before.

  Recruiting at 5 sites Phase 2 Hoosier Cancer Research Network · Indianapolis, Indiana and 4 other locations · NCT06493019

• Combining Adagrasib with Stereotactic Radiosurgery for Brain Metastases in Lung Cancer

  This study is testing whether combining a targeted therapy called adagrasib with a type of focused radiation treatment can help people with lung cancer that has spread to the brain feel better.

  Recruiting at 3 sites Phase 2 Hoosier Cancer Research Network · Columbus, Ohio and 2 other locations · NCT06248606

• Comparing brain radiotherapy timing in lung cancer patients with ALK rearrangements

  This study is testing whether a targeted lung cancer treatment called alectinib works better alone or with brain radiation for patients who have lung cancer with specific genetic changes and brain metastases.

  Recruiting at 3 sites Phase 1/2 Hoosier Cancer Research Network · Stanford, California and 2 other locations · NCT05987644

• Combination treatment for extensive stage small cell lung cancer

  This study is testing a new combination treatment for people with extensive stage small cell lung cancer to see if it helps them live longer and feel better.

  Recruiting at 4 sites Phase 2 Hoosier Cancer Research Network · Indianapolis, Indiana and 3 other locations · NCT05903092

• Combination therapy for relapsed large cell lymphoma using epcoritamab and chemotherapy

  This study is testing a new combination of treatments for people with relapsed large cell lymphoma to see if it helps them respond better after previous therapies.

  Recruiting at 4 sites Phase 2 Hoosier Cancer Research Network · Indianapolis, Indiana and 3 other locations · NCT05852717

• Ribociclib and hormone therapy for recurrent breast cancer

  This study is testing if a new drug called ribociclib, when combined with hormone therapy, can help people with recurrent hormone receptor-positive breast cancer feel better and manage their condition.

  Recruiting at 19 sites Phase 2 Hoosier Cancer Research Network · Birmingham, Alabama and 20 other locations · NCT05467891

• Combination treatment for newly diagnosed secondary acute myeloid leukemia

  This study is testing a new combination of treatments for people with newly diagnosed secondary acute myeloid leukemia to see if it helps them respond better and live longer.

  Recruiting at 7 sites Phase 2 Hoosier Cancer Research Network · Miami, Florida and 6 other locations · NCT05442216

• Pre-operative treatment for HER2-positive, ER-positive breast cancer

  This study is testing if a new combination of treatments can help women with HER2-positive, ER-positive breast cancer before they have surgery.

  Recruiting at 4 sites Phase 2 Hoosier Cancer Research Network · Chicago, Illinois and 3 other locations · NCT04886531

Quick answers

How many clinical trials run by Hoosier Cancer Research Network are recruiting right now?

18, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 16, Phase 1/2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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