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Clinical trials and research at Eastern Cooperative Oncology Group

• 16Clinical trials
• 6Countries

Newest trials

All recruiting trials (16)

• Daratumumab-hyaluronidase added to your myeloma treatment to see if it helps kidney function

  This trial tests whether adding daratumumab-hyaluronidase to the standard bortezomib and dexamethasone therapy improves kidney function in adults newly diagnosed with multiple myeloma and kidney failure.

  Recruiting Phase 2 Eastern Cooperative Oncology Group · Anchorage, Alaska · NCT07085728

• Older adults with early-stage melanoma: WLE alone vs. WLE with SLN biopsy

  This trial tests whether doing wide local excision alone works as well as the standard approach of WLE plus sentinel lymph node biopsy for older adults with early-stage melanoma.

  Recruiting at 176 sites Phase 3 Eastern Cooperative Oncology Group · Birmingham, Alabama and 180 other locations · NCT07068074

• Sulforaphane to help prevent new melanomas in people with many atypical moles and a history of melanoma

  This phase 2 trial tests whether taking sulforaphane daily can help prevent new melanomas in people with multiple atypical nevi and a prior melanoma history.

  Recruiting Phase 2 Eastern Cooperative Oncology Group · Pittsburgh, Pennsylvania · NCT07040280

• Adding paclitaxel into the abdominal cavity for gastric cancer that has spread to the peritoneum

  This trial will try adding paclitaxel delivered directly into the abdomen to standard IV chemotherapy for people with gastric or gastroesophageal junction cancer that has spread to the lining of the abdominal cavity to see if it slows disease growth and helps them live longer.

  Recruiting at 78 sites Phase 2/3 Eastern Cooperative Oncology Group · Irvine, California and 77 other locations · NCT07001748

• Improving cancer trial enrollment for Black and Latino patients

  This study is testing a new support program to help Black and Latino cancer patients learn about and join clinical trials more easily.

  Recruiting at 67 sites Eastern Cooperative Oncology Group · Jonesboro, Arkansas and 66 other locations · NCT06756607

• High-dose chemotherapy with autologous stem cell transplant versus observation for peripheral T‑cell lymphoma in complete remission

  This trial tests whether giving high‑dose chemotherapy followed by the patient's own stem cell transplant helps adults with peripheral T‑cell lymphoma who are in complete remission stay cancer‑free longer than observation alone.

  Recruiting at 142 sites Phase 3 Eastern Cooperative Oncology Group · Birmingham, Alabama and 164 other locations · NCT06724237

• Comparing targeted therapy and chemotherapy for thyroid cancer

  This study is testing whether a new targeted therapy works better than standard chemotherapy for patients with a specific type of thyroid cancer that has a BRAF V600E mutation.

  Recruiting at 289 sites Phase 3 Eastern Cooperative Oncology Group · Anchorage, Alaska and 306 other locations · NCT06475989

• Improving predictions for brain cancer progression using advanced imaging techniques

  This study is testing whether new imaging techniques can help doctors better understand how glioblastoma tumors are behaving and improve treatment for patients who have just been diagnosed.

  Recruiting at 16 sites Phase 2 Eastern Cooperative Oncology Group · Birmingham, Alabama and 17 other locations · NCT06319027

• Helping cancer patients manage costs and financial stress

  This study is testing a new program to help cancer patients manage their costs and financial stress to see if it improves their ability to stick to treatment and their overall quality of life.

  Recruiting at 363 sites Eastern Cooperative Oncology Group · Anchorage, Alaska and 390 other locations · NCT06295367

• Testing pump chemotherapy for liver metastases from colorectal cancer

  This study is testing if adding a special type of chemotherapy delivered directly to the liver can help people with colorectal cancer that has spread to the liver live longer and have fewer problems compared to standard chemotherapy alone.

  Recruiting at 54 sites Phase 3 Eastern Cooperative Oncology Group · Birmingham, Alabama and 61 other locations · NCT05863195

• Using daratumumab to treat T-cell leukemia that doesn't respond to chemotherapy

  This study is testing if daratumumab can help T-cell leukemia patients who haven't responded to chemotherapy by seeing if it clears their cancer and improves their chances of staying healthy.

  Recruiting Phase 2 Eastern Cooperative Oncology Group · Chicago, Illinois · NCT05289687

• Combining four drugs to treat newly diagnosed multiple myeloma

  This study is testing if adding a fourth drug to a three-drug treatment helps adults with newly diagnosed multiple myeloma live longer and feel better.

  Recruiting at 303 sites Phase 3 Eastern Cooperative Oncology Group · Anchorage, Alaska and 646 other locations · NCT04566328

• Combining Apalutamide and Targeted Radiation for Recurrent Prostate Cancer

  This study is testing if combining a new medication with radiation therapy can help men with recurring prostate cancer feel better and live longer after surgery.

  Recruiting at 278 sites Phase 3 Eastern Cooperative Oncology Group · Anchorage, Alaska and 340 other locations · NCT04423211

• Comparing two ways to monitor pancreatic cysts

  This trial tests whether more frequent or less frequent imaging is better for people aged 50–75 who have one or more pancreatic cysts ≥1 cm.

  Recruiting at 344 sites Eastern Cooperative Oncology Group · Birmingham, Alabama and 428 other locations · NCT04239573

• Combining lenalidomide and dexamethasone with or without daratumumab for high-risk smoldering myeloma

  This study is testing if adding daratumumab to the standard treatment of lenalidomide and dexamethasone can help people with high-risk smoldering multiple myeloma live longer and feel better.

  Recruiting at 489 sites Phase 3 Eastern Cooperative Oncology Group · Birmingham, Alabama and 747 other locations · NCT03937635

• Comparing radiation therapy alone or with cisplatin for advanced head and neck cancer after surgery

  This study is testing whether adding the chemotherapy drug cisplatin to radiation therapy helps people with advanced head and neck cancer feel better after surgery compared to just radiation alone.

  Recruiting at 463 sites Phase 2 Eastern Cooperative Oncology Group · Birmingham, Alabama and 678 other locations · NCT02734537

Quick answers

How many clinical trials run by Eastern Cooperative Oncology Group are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (16 trials), Puerto Rico (4 trials), Mexico (1 trial), Guam (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 7, Phase 2: 5, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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