Sponsor or institution
Clinical trials and research at Denali Therapeutics Inc.
As of November 12, 2026, Find a Trial lists 4 clinical trials run by Denali Therapeutics Inc. that are recruiting, at sites in 3 countries (most in United Kingdom (2), United States (2), Netherlands (1)). By phase: Phase 1 (3), Phase 1/2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 3Countries
Newest trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| DNL921 safety and pharmacology in healthy adults and people with Alzheimer's disease | Phase 1 | Manchester | Recruiting | Aug 11, 2026 |
| DNL952 treatment for adults with late-onset Pompe disease | Phase 1 | Irvine, California and 3 other locations | Recruiting | Jan 21, 2026 |
| DNL628 safety, tolerability, and drug behavior in people with early Alzheimer's disease. | Phase 1 | 's-Hertogenbosch and 3 other locations | Recruiting | Jan 9, 2026 |
| Treatment for children with Sanfilippo Syndrome Type A using DNL126 | Phase 1/2 | Oakland, California and 3 other locations | Recruiting | Dec 26, 2023 |
All recruiting trials (4)
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DNL921 safety and pharmacology in healthy adults and people with Alzheimer's disease
This study tests how DNL921 behaves in the body and whether it is safe in healthy adults and in people with Alzheimer's disease.
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DNL952 treatment for adults with late-onset Pompe disease
This Phase 1 trial will test DNL952 in adults with late-onset Pompe disease to see if it is safe and how the drug is handled by the body.
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DNL628 safety, tolerability, and drug behavior in people with early Alzheimer's disease.
This trial will test DNL628 versus placebo in people with early Alzheimer's disease to see if it is safe, well tolerated, and how the body handles the drug.
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Treatment for children with Sanfilippo Syndrome Type A using DNL126
This study is testing a new treatment called DNL126 to see if it can help children with Sanfilippo Syndrome Type A feel better and improve their condition.
Quick answers
How many clinical trials run by Denali Therapeutics Inc. are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United Kingdom (2 trials), United States (2 trials), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 3, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.