Sponsor or institution

Clinical trials and research at Centre de Recherche de L'hopital Douglas

• 5NIH research projects

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Single-cell study of mood-regulation brain circuits in depression

  A large study will map which genes and cell types in mood-related brain circuits are linked to major depressive disorder, including differences by ancestry and sex.

  NIH research Centre de Recherche de L'hopital Douglas · Montreal, Canada · NIH-11421431

• Imaging the brain's endocannabinoid system in young people with depression or suicidal behavior

  The team will use PET brain scans to measure an enzyme that controls natural cannabis-like chemicals in teens and young adults with depression, some with past suicide attempts.

  NIH research Centre de Recherche de L'hopital Douglas · Montreal, Canada · NIH-11251610

• Mapping cell and gene changes in the brain linked to depression

  Mapping genes and cell types in key mood-regulating brain regions from people with major depressive disorder, including diverse ancestries and both sexes.

  NIH research Centre de Recherche de L'hopital Douglas · Montreal, Canada · NIH-11184481

• Exploring how endocannabinoid metabolism relates to depression and suicide in young people

  This study is looking at how a specific system in the body might affect feelings of sadness and thoughts of suicide in teens aged 12 to 20, focusing on a particular enzyme that could change how we feel and act, with the hope of finding new ways to help those struggling with these issues.

  NIH research Centre de Recherche de L'hopital Douglas · Montreal, Canada · NIH-11124206

• Investigating the role of endocannabinoid metabolism in early psychosis and schizophrenia

  This study is looking at how changes in a system in the brain that uses natural chemicals called endocannabinoids might play a role in developing schizophrenia, especially for those who are at high risk or having their first episode of psychosis, to find new ways to help prevent and treat the condition.

  NIH research Centre de Recherche de L'hopital Douglas · Montreal, Canada · NIH-10707675

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