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Clinical trials and research at Cancer Research UK

• 12Clinical trials
• 1Country

Newest trials

All recruiting trials (12)

• Dabrafenib and trametinib for rare cancers with BRAF V600 mutations

  This arm tests whether dabrafenib and trametinib can help adults, children, and teens with cancers that have a BRAF V600 mutation.

  Recruiting at 15 sites Phase 2/3 Cancer Research UK · Belfast and 26 other locations · NCT07440290

• Capmatinib treatment for adults with cancers having MET gene changes

  This study is testing if capmatinib, a drug for lung cancer, can help adults with different types of cancers that have changes in the MET gene.

  Recruiting at 16 sites Phase 2/3 Cancer Research UK · Belfast and 16 other locations · NCT06988475

• Testing UCB4594 for advanced cancer treatment

  This study is testing a new drug called UCB4594 to see if it can help treat advanced cancer by targeting a specific protein on cancer cells.

  Recruiting at 3 sites Phase 1/2 Cancer Research UK · London and 3 other locations · NCT06380816

• Treatment of B-cell malignancies with ALETA-001

  This study is testing a new treatment called ALETA-001 to see if it can help people with relapsed non-Hodgkin lymphoma who didn't respond well to previous therapies.

  Recruiting at 6 sites Phase 1/2 Cancer Research UK · Birmingham and 6 other locations · NCT06045910

• Evaluating HTL0039732 for Advanced Solid Tumours

  This study is testing a new drug called HTL0039732, alone and with another treatment, to see if it can help people with advanced solid tumors by boosting their immune response against cancer.

  Recruiting at 6 sites Phase 1/2 Cancer Research UK · Cambridge and 5 other locations · NCT05944237

• Combination of trastuzumab and pertuzumab for treating cancers with HER2 mutations

  This study is testing if a combination of two cancer drugs, trastuzumab and pertuzumab, can help adults and young people with cancers that have HER2 mutations or amplifications.

  Recruiting at 24 sites Phase 2/3 Cancer Research UK · Belfast and 26 other locations · NCT05786716

• Entrectinib treatment for patients with ROS1-positive cancers

  This study is testing if the drug entrectinib can help people with different types of cancers that have a ROS1 gene fusion, including adults and kids, to see if it works better than what’s currently available.

  Recruiting at 24 sites Phase 2/3 Cancer Research UK · Belfast and 26 other locations · NCT05770544

• Using atezolizumab to treat cancers with high mutation rates or specific genetic deficiencies

  This study is testing if atezolizumab can help treat adults and kids with certain types of cancers that have a lot of genetic changes or specific genetic issues.

  Recruiting at 23 sites Phase 2/3 Cancer Research UK · Belfast and 26 other locations · NCT05770102

• Alectinib treatment for ALK-positive cancers in adults and children

  This study is testing if alectinib, a drug for lung cancer, can help treat different types of ALK-positive cancers in both adults and children.

  Recruiting at 24 sites Phase 2/3 Cancer Research UK · Belfast and 26 other locations · NCT05770037

• Combination of vemurafenib and cobimetinib for treating BRAF positive cancers

  This study is testing if the combination of vemurafenib and cobimetinib can help adults with different types of cancers that have a specific BRAF mutation.

  Recruiting at 16 sites Phase 2/3 Cancer Research UK · Belfast and 15 other locations · NCT05768178

• Evaluating existing drugs for rare cancers with specific genetic changes

  This study is testing if approved cancer drugs can help people with rare cancers or common cancers that have specific genetic changes feel better and live longer.

  Recruiting at 26 sites Phase 2/3 Cancer Research UK · Belfast and 26 other locations · NCT05722886

• Evaluating TT-702 for advanced solid tumors

  This study is testing a new drug called TT-702 to see if it can safely help people with advanced solid tumors, including certain types of prostate cancer and breast cancer, by boosting their immune response.

  Recruiting at 3 sites Phase 1/2 Cancer Research UK · London and 2 other locations · NCT05272709

Quick answers

How many clinical trials run by Cancer Research UK are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United Kingdom. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 8, Phase 1/2: 4. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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