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Clinical trials and research at Alto Neuroscience

• 4Clinical trials
• 2Countries

Newest trials

All recruiting trials (4)

• ALTO-207 for adults with treatment-resistant depression

  This trial will test whether ALTO-207 reduces depressive symptoms more than placebo in adults whose depression has not improved after at least two antidepressant treatments.

  Recruiting at 40 sites Phase 2 Alto Neuroscience · Dothan, Alabama and 62 other locations · NCT07553637

• Evaluating ALTO-100 for treating depression in bipolar disorder

  This study is testing if a new medication called ALTO-100 can help people with bipolar disorder who are having a major depressive episode feel better compared to a placebo.

  Recruiting at 49 sites Phase 2 Alto Neuroscience · Birmingham, Alabama and 67 other locations · NCT06656416

• Evaluating ALTO-101 for cognitive impairment in schizophrenia

  This study is testing a new skin patch called ALTO-101 to see if it can help improve thinking skills in people with schizophrenia.

  Recruiting at 13 sites Phase 2 Alto Neuroscience · Garden Grove, California and 13 other locations · NCT06502964

• Evaluating ALTO-300 for treating major depressive disorder

  This study is testing if adding ALTO-300 to standard antidepressants can help people with moderate to severe depression feel better compared to a placebo.

  Recruiting at 30 sites Phase 2 Alto Neuroscience · Phoenix, Arizona and 74 other locations · NCT05922878

Quick answers

How many clinical trials run by Alto Neuroscience are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (4 trials), United Kingdom (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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