Sponsor or institution

Clinical trials and research at Agios Pharmaceuticals, Inc.

• 4Clinical trials
• 2Countries

Newest trials

All recruiting trials (4)

• Mitapivat for reducing transfusion needs in sickle cell disease

  This study tests whether mitapivat, compared with placebo, can lower the number of blood transfusions needed by people with sickle cell disease.

  Recruiting at 5 sites Phase 3 Agios Pharmaceuticals, Inc. · Indianapolis, Indiana and 4 other locations · NCT07656415

• Mitapivat for pediatric non-transfusion-dependent alpha- or beta-thalassemia

  This study tests whether mitapivat helps reduce anemia in children with non-transfusion-dependent alpha- or beta-thalassemia compared with placebo.

  Recruiting at 5 sites Phase 3 Agios Pharmaceuticals, Inc. · Palo Alto, California and 4 other locations · NCT07517133

• Mitapivat for pediatric transfusion-dependent thalassemia (α- or β-TDT)

  This pediatric trial tests whether mitapivat can reduce or lessen the need for transfusions in children with transfusion-dependent alpha- or beta-thalassemia.

  Recruiting at 4 sites Phase 3 Agios Pharmaceuticals, Inc. · Atlanta, Georgia and 3 other locations · NCT07506863

• AG-181 safety and tolerability in people with phenylketonuria

  This trial will test AG-181 for safety and tolerability in people with PKU who have high blood phenylalanine and at least one R408W PAH mutation.

  Recruiting at 5 sites Phase 1 Agios Pharmaceuticals, Inc. · Indianapolis, Indiana and 4 other locations · NCT07241234

Quick answers

How many clinical trials run by Agios Pharmaceuticals, Inc. are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (4 trials), Poland (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 3, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →