Sponsor or institution
Clinical trials and research at 4D Molecular Therapeutics
As of November 12, 2026, Find a Trial lists 5 clinical trials run by 4D Molecular Therapeutics that are recruiting, at sites in 20 countries (most in United States (4), Japan (2), Puerto Rico (2)). By phase: Phase 3 (2), Phase 1/2 (2), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 20Countries
Newest trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| 4D-150 gene therapy injected into the eye for adults with diabetic macular edema | Phase 3 | Scottsdale, Arizona and 93 other locations | Recruiting | Oct 9, 2026 |
| Single intravitreal injection of 4D-150 for macular neovascularization from age-related macular degeneration | Phase 3 | Scottsdale, Arizona and 125 other locations | Recruiting | Jul 15, 2025 |
| Treatment for adults with Fabry disease and heart issues | Phase 1/2 | Melbourne and 3 other locations | Recruiting | Nov 29, 2022 |
| Investigational gene therapy for adults with cystic fibrosis | Phase 2 | Birmingham, Alabama and 19 other locations | Recruiting | Feb 21, 2022 |
| Treatment for wet age-related macular degeneration using 4D-150 | Phase 1/2 | Phoenix, Arizona and 25 other locations | Recruiting | Jan 19, 2022 |
All recruiting trials (5)
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4D-150 gene therapy injected into the eye for adults with diabetic macular edema
This study tests whether a one-time intravitreal injection of 4D-150 can help adults with diabetic macular edema compare to aflibercept.
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Single intravitreal injection of 4D-150 for macular neovascularization from age-related macular degeneration
This trial will try a single eye injection of 4D-150 versus standard aflibercept in adults 50 and older with neovascular (wet) AMD to see if it controls disease activity.
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Treatment for adults with Fabry disease and heart issues
This study is testing a new treatment for adults with Fabry disease and heart problems to see if it is safe and how well it works.
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Investigational gene therapy for adults with cystic fibrosis
This study is testing a new gene therapy for adults with cystic fibrosis who have severe lung disease and can't use current treatments, to see if it helps improve their health.
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Treatment for wet age-related macular degeneration using 4D-150
This study is testing a new gene therapy called 4D-150 to see if it can improve vision in adults with wet age-related macular degeneration who are already receiving other treatments.
Quick answers
How many clinical trials run by 4D Molecular Therapeutics are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 20 countries. The most sites are in United States (4 trials), Japan (2 trials), Puerto Rico (2 trials), Australia (2 trials), China (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 2, Phase 1/2: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.