Zimbabwe–UCSF HIV Clinical Trials Unit
UZ-UCSF CTU
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11423437
Testing new and existing HIV prevention and treatment approaches with adults and children in Zimbabwe to improve care.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-11423437 on ClinicalTrials.gov |
What this research studies
This clinical trials unit runs and manages Phase I–IV HIV and TB trials at multiple clinic sites in Zimbabwe in partnership with UCSF and international NIH networks. It enrolls adults, adolescents, and children into trials testing ARV-based treatments and prevention approaches, collects clinical data and samples, and follows participants through scheduled visits. The CTU trains local research staff, manages data and laboratory work, and adapts operations to local challenges to keep trials safe and reliable. Work spans multiple NIH-funded networks (ACTG, IMPAACT, HPTN, HVTN) so studies can include vaccines, new drugs, and prevention strategies, and trial results help inform Zimbabwe’s health policy and standards of care.
Who could benefit from this research
Good fit: Adults, adolescents, and children in Zimbabwe who are living with or at risk for HIV (and sometimes TB) and who can attend clinic visits are the ideal candidates.
Not a fit: People with health issues unrelated to HIV or TB, or those who cannot travel to the CTU clinic sites in Zimbabwe, are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, the work could lead to safer, more effective HIV prevention and treatment options and improved care practices for people in Zimbabwe and beyond.
How similar studies have performed: Numerous past ACTG, HPTN, IMPAACT, and HVTN trials have led to important HIV prevention and treatment advances, so this builds on well-established, successful approaches.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHIRENJE, ZVAVAHERA MIKE — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: CHIRENJE, ZVAVAHERA MIKE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus