NIH-funded research NIH-funded research

Zero Cavity: A smartphone approach to keep young teeth cavity-free

Official title: Innovative mHealth Intervention providing Sustained Anticipatory Guidance (Zero Cavity): Design, Validation, User Perception, and Effectiveness

Funded at Sri Ramachandra Institute of Higher Education and Research Trust · NIH-11393346 · Data updated 2026-11-12

A smartphone app delivers ongoing guidance to caregivers of young children to help prevent tooth decay.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionSri Ramachandra Institute of Higher Education and Research Trust
NIH-funded
Lab location1 site (Chennai, India)
Project startSeptember 15, 2023
Project endMay 31, 2028
Funding year2026
Award (this year)$181,295
NIH project number5R33TW012359-04
Project IDNIH-11393346 on NIH RePORTER

Who could benefit from this research

Could help

Caregivers of children aged 0-11 who use Android or iOS devices and are willing to participate in a caregiver-child program.

Less likely to help

Families not using smartphones or without access to the required devices may receive limited benefit.

What this research studies

This project uses a mobile app called Zero Cavity to provide continuous tips on oral hygiene, diet, fluoride use, and care for children aged 0-11. In the United States and India partnership, families will be randomly assigned to receive either standard guidance or standard guidance plus the app’s sustained anticipatory guidance, with follow-ups over time. The study will measure the app’s impact on overall health guidance adherence and the occurrence of early childhood caries using real-world dental assessments. Results could inform how digital tools support long-term preventive care for kids’ teeth.

Why it matters

Potential benefit: If successful, caregivers could have a practical tool to help reduce early childhood caries and improve daily oral health habits for their children.

How similar studies have gone: Digital, reminder-based oral health tools have shown promise in improving adherence, with this study testing a sustained, guided approach across a large sample.

Where this research is happening

  • Sri Ramachandra Institute of Higher Education and Research Trust
    Chennai, India
    Active

Researchers

  • Principal investigator: Murugan, Muthu Satta — Sri Ramachandra Institute of Higher Education and Research Trust
  • Study coordinator: Murugan, Muthu Satta

Related research

Other NIH-funded projects on the same topics.

  • Zero Cavity: a smartphone app that helps parents prevent tooth decay in young children

    A mobile app that sends age‑appropriate tips and reminders to parents to help prevent cavities in babies and young children.

    NIH research Sri Ramachandra Institute of Higher Education and Research Trust · Chennai, India · NIH-11351610

  • Mobile app to help prevent tooth decay in young children

    This study is testing a friendly mobile app called Zero Cavity that helps parents of kids aged 0-11 learn how to prevent tooth decay by giving them useful tips and advice about oral health.

    NIH research Sri Ramachandra Institute of Higher Education and Research Trust · Chennai, India · NIH-10930898

  • The effects of air pollution on birthweight in pregnant women in Chennai, India.

    This study is looking at how air pollution, specifically tiny particles and certain chemicals, might affect the weight of babies at birth, and it's for pregnant women in Chennai who want to understand how their environment could impact their baby's health.

    NIH research Sri Ramachandra Institute of Higher Education and Research Trust · Chennai, India · NIH-10879106

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.