Yale macaque brain tissue resource for learning about the human brain
Yale Macaque Brain Resource
Yale is preserving and expanding a large collection of macaque brain tissues so scientists can learn more about how the human brain develops and is changed by injury or disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11224084 on NIH RePORTER |
What this research studies
From a patient perspective, Yale maintains a decades-old collection of monkey brain samples spanning embryonic to adult ages, prepared in many ways (cell birthdating, tract tracing, lesions, electron microscopy, and immunohistochemistry). The project is cataloguing, restoring, and adding materials while processing more tissue for modern analyses. Yale makes these samples and detailed records available to other scientists so they can compare normal and abnormal brain development and pathology. By organizing and sharing these rare materials, researchers everywhere can study mechanisms relevant to human brain disorders without repeating the same animal work.
Who could benefit from this research
Good fit: No patients are enrolled in this grant; the resource primarily supports researchers studying human brain development and neurological disorders.
Not a fit: Individuals seeking direct clinical care or enrollment in a treatment trial will not receive direct benefit from this tissue-collection project.
Why it matters
Potential benefit: If successful, the resource could speed discoveries about brain development and disease mechanisms that eventually lead to better diagnostics and treatments.
How similar studies have performed: Other primate and human brain tissue collections have been valuable for understanding brain development and disease, although translating those findings into new treatments typically takes time.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Duque, Alvaro — Yale University
- Study coordinator: Duque, Alvaro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.