Women’s choices and outcomes with injectable and oral HIV prevention in Malawi

Better Info on Women's PrEP Choices and Outcomes in Malawi

NIH-funded research Johns Hopkins University · NIH-11394649

This project follows women in Malawi offered long-acting injectable PrEP or daily oral PrEP to learn which options they prefer, how often they switch, and how long they continue protection.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11394649 on NIH RePORTER

What this research studies

You would be followed as clinics in Malawi roll out injectable PrEP alongside oral PrEP through an existing program called PathToScale. The study will use clinic records, surveys, and targeted follow-up (including tracing people who stop PrEP) to track patterns of use over time. Researchers will ask about reasons for choosing, switching, or stopping products and record related health outcomes. The focus is on capturing real-world experiences during the early expansion of these prevention options.

Who could benefit from this research

Good fit: Women in Malawi who are eligible for HIV prevention and who are offered oral or injectable PrEP at participating clinics in the PathToScale rollout.

Not a fit: People outside the participating Malawi clinics, men, or women not offered PrEP through the rollout would not directly benefit from taking part.

Why it matters

Potential benefit: If successful, the findings could help clinics provide better information and support so more women can choose and stay on the HIV prevention option that fits them.

How similar studies have performed: Clinical trials have shown long-acting injectable PrEP to be highly effective, but large-scale real-world studies of women's choices and continuation in routine programs are limited.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.