Why some people don't notice mistakes after a left-side stroke
Factors contributing to unawareness of performance errors after left hemisphere stroke
This project tests whether problems sensing arm movement, remembering actions, or paying attention explain why people with left-hemisphere stroke don't notice errors when using their arm.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thomas Jefferson University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11295088 on NIH RePORTER |
What this research studies
You would be asked to perform everyday tasks with your affected arm while researchers record the errors you make and whether you notice them. The team will measure body sensing (proprioception), memory/representation of actions, and attention/monitoring during these tasks. They will link those behavioral measures to brain imaging or lesion data to find biological markers of error unawareness. Findings aim to show how sensation, cognition, and brain changes combine to cause unawareness and guide better rehab strategies.
Who could benefit from this research
Good fit: Adults who have had a left-hemisphere stroke and who have trouble using their arm or who may not notice errors during everyday tasks are the best fit.
Not a fit: People without left-hemisphere stroke, those whose problems are unrelated to limb apraxia, or those unable to travel to the study site are unlikely to benefit from participating.
Why it matters
Potential benefit: If successful, this work could help clinicians identify who is unaware of arm-use errors and tailor rehabilitation to improve safety, independence, and reduce caregiver burden.
How similar studies have performed: Previous work has documented unawareness of limb apraxia and linked proprioception and attention to awareness in small studies, but combining naturalistic tasks with brain markers is a relatively new approach.
Where this research is happening
Philadelphia, United States
- Thomas Jefferson University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Wong, Aaron L — Thomas Jefferson University
- Study coordinator: Wong, Aaron L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.