Why some African American cancer survivors develop new cancers
Project 2
['FUNDING_P01'] · WAYNE STATE UNIVERSITY · NIH-11287874
This project looks at why African American survivors of breast, prostate, or colorectal cancer sometimes get a second, separate cancer and what factors raise that risk.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WAYNE STATE UNIVERSITY (nih funded) |
| Locations | 1 site (DETROIT, UNITED STATES) |
| Trial ID | NIH-11287874 on ClinicalTrials.gov |
What this research studies
The team will use participants from the Detroit ROCS cohort—African American adults who survived breast, prostate, or colorectal cancer—and compare those who later developed a new primary cancer with those who did not. They will combine medical records, blood-based biological tests, genetic data, and participant surveys about lifestyle and exposures to identify possible causes. The project examines inherited risk, treatment-related effects, and environmental or behavioral contributors to second cancers. Results will be used to guide ideas for earlier detection and risk-reduction for survivors.
Who could benefit from this research
Good fit: African American adults who previously had breast, prostate, or colorectal cancer—especially survivors in the Detroit ROCS cohort or those living in the Detroit area—are the primary candidates.
Not a fit: People without a history of these cancers, non-African American individuals, or those with unrelated cancer types are unlikely to benefit directly from this specific project.
Why it matters
Potential benefit: If successful, this work could help identify survivors at higher risk for second cancers so they can get closer monitoring or preventive care.
How similar studies have performed: Prior studies have shown that about 10% of survivors develop a second primary cancer and Detroit ROCS has been used before, but this focused combination of genetics, biology, and exposure data in African American survivors is relatively new.
Where this research is happening
DETROIT, UNITED STATES
- WAYNE STATE UNIVERSITY — DETROIT, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BEEBE-DIMMER, JENNIFER L — WAYNE STATE UNIVERSITY
- Study coordinator: BEEBE-DIMMER, JENNIFER L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.