Why self-control feels costly: brain and emotion links

Neural and affective mechanisms underlying prospective self-control costs

NIH-funded research New York University School of Medicine · NIH-11323055

This project measures how much people who struggle with temptations will pay to avoid them and looks at the brain and emotional signals tied to those choices.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University School of Medicine NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11323055 on NIH RePORTER

What this research studies

You would take part in decision tasks that measure how much you prefer to block access to tempting rewards (precommitment) rather than face the temptation. The team will use a refined behavioral task plus brain imaging to find the mental computations and emotional responses that make self-control feel costly. They will test how stress changes those signals and compare task behavior to real-world self-control slips reported by participants. The goal is to map which brain regions and feelings predict when people give in or successfully stick to long-term goals.

Who could benefit from this research

Good fit: Adults who find it hard to resist temptations (for example around food, spending, or substance use) and who are willing to do decision tasks and brain imaging would be ideal candidates.

Not a fit: People who cannot undergo MRI (for example due to metal implants, claustrophobia, or pregnancy) or who are unable or unwilling to complete decision-making tasks may not benefit or be able to participate.

Why it matters

Potential benefit: If successful, this work could point to new targets for treatments or strategies that make it easier to stick with goals like healthy eating, saving money, or avoiding substances.

How similar studies have performed: Related precommitment tasks and neuroimaging studies have linked self-control to specific brain systems, but measuring a formal 'cost function' for self-control and how stress alters it is a newer approach.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.