Why many young adults naturally reduce heavy drinking

Neural mechanisms of maturing out of problem alcohol use

NIH-funded research University of Michigan at Ann Arbor · NIH-11127667

This study looks at how brain changes in 21–25-year-olds who binge drink might help some people cut back on heavy drinking while others keep drinking.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11127667 on NIH RePORTER

What this research studies

You would join 400 people aged 21–25 who report at least one binge-drinking episode per month. You will have high-resolution structural and functional MRI scans while doing tasks that measure thinking control, emotion regulation, responses to alcohol cues, and resting-state brain activity. The team will track your drinking and related behaviors over time to see who naturally reduces heavy drinking and who does not. Researchers will link patterns of brain maturation to changes in real-world drinking.

Who could benefit from this research

Good fit: Ideal participants are adults aged 21–25 who have had at least one binge drinking episode per month for the past three months and can attend MRI visits in Ann Arbor.

Not a fit: People outside the 21–25 age range, those who do not binge drink regularly, or those already in intensive treatment for severe alcohol use disorder are less likely to benefit from this project.

Why it matters

Potential benefit: If successful, this work could identify brain patterns that predict who will stop heavy drinking naturally and help target prevention or early interventions.

How similar studies have performed: Prior imaging studies have linked brain development to risky behavior, but directly connecting brain maturation to 'maturing out' of heavy drinking in a large longitudinal sample is largely new.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.