Why cancer deaths are higher in rural communities

Understanding rural mortality disparities in cancer: a multi-level approach

NIH-funded research Brigham and Women's Hospital · NIH-11469037

This project looks at cancer death rates and local social, economic, and health-care factors to understand why people with cancer in rural areas often have worse outcomes than those in cities.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11469037 on NIH RePORTER

What this research studies

If you or someone you know has cancer, researchers will use national cancer registry records to compare survival and death rates across different ways of defining 'rural.' They will link those records to many county-level sources—like the Census, Area Deprivation Index, employment, and local health workforce data—to see which community factors relate to worse outcomes. The team will use multi-level statistical methods to separate what is due to individual circumstances and what comes from living in certain places. The goal is to point to geographic or social drivers that could be changed to improve cancer care and survival in rural areas.

Who could benefit from this research

Good fit: People diagnosed with breast cancer (and other cancers) who live in U.S. rural counties covered by SEER would be the population whose records are analyzed and who could benefit from future interventions.

Not a fit: Patients who live outside SEER-covered regions, outside the U.S., or who are not captured in cancer registries may not be included and therefore not directly benefit from this project's findings.

Why it matters

Potential benefit: If successful, the work could guide targeted programs and policies to reduce higher cancer deaths in rural communities.

How similar studies have performed: Previous research has documented rural–urban gaps in cancer outcomes, but few projects have linked this many county-level datasets and tested multiple rural definitions, making this approach more comprehensive and relatively novel.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Breast Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.