Whole‑body PET that maps how cancers use glucose
Total-body PET Parametric Imaging using Relative Patlak Plot
['FUNDING_R03'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-11291878
This project develops a faster way to use whole‑body FDG PET scans to create detailed maps showing how cancers use sugar for people with cancer.
Quick facts
| Phase | ['FUNDING_R03'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA AT DAVIS (nih funded) |
| Locations | 1 site (DAVIS, UNITED STATES) |
| Trial ID | NIH-11291878 on ClinicalTrials.gov |
What this research studies
You would benefit from clearer maps of how tumors use glucose that can help doctors understand tumor activity. The team will use total‑body PET scanners and a new "relative Patlak" mathematical approach to produce parametric images (maps of metabolic rate) without needing very long dynamic scans. They will compare the new method to the standard Patlak approach to confirm the maps match established measures. The goal is shorter, more sensitive scans that still give reliable metabolic information.
Who could benefit from this research
Good fit: People with known or suspected cancer who are getting FDG PET imaging and can access a center with a total‑body PET scanner would be ideal candidates.
Not a fit: Patients whose tumors do not take up FDG, who cannot undergo PET scans, or who cannot travel to centers with total‑body PET scanners are unlikely to benefit directly from this project.
Why it matters
Potential benefit: If successful, this could give faster, more accurate metabolic maps that help guide cancer diagnosis and treatment decisions while shortening scan time.
How similar studies have performed: Standard Patlak parametric imaging and recent total‑body PET work have shown promise for better metabolic measures, but applying a "relative Patlak" method to shorten scans is a newer approach with limited patient testing so far.
Where this research is happening
DAVIS, UNITED STATES
- UNIVERSITY OF CALIFORNIA AT DAVIS — DAVIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LI, SIQI — UNIVERSITY OF CALIFORNIA AT DAVIS
- Study coordinator: LI, SIQI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Treatment