Where antibiotic-resistant gut bacteria live in our communities
Community Reservoirs of Extended-Spectrum Beta-Lactamase-producing and Multi-Drug Resistant Enterobacterales
Researchers will look for antibiotic-resistant Enterobacterales in people, animals, and the environment to help protect children and adults in affected neighborhoods.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11140484 on NIH RePORTER |
What this research studies
This project will collect samples from people (including children and adults), household animals, and local environments in different Chicago neighborhoods to find antibiotic-resistant Enterobacterales. Scientists will use genetic testing to compare bacterial strains and antibiotic resistance genes from those samples to strains that cause community infections. By mapping where resistant bacteria and resistance genes are found and how they move between sources, the team aims to pinpoint likely reservoirs and transmission pathways. The work includes community recruitment, sample collection, lab sequencing, and multi-year data analysis.
Who could benefit from this research
Good fit: People of all ages who live in the Chicago neighborhoods included in the study, including children and adults willing to provide samples and health information, are the likely candidates.
Not a fit: People who do not live in the targeted communities or whose infections are caused by unrelated bacteria are unlikely to directly benefit from participating.
Why it matters
Potential benefit: Could help prevent community-acquired antibiotic-resistant infections by guiding targeted public health actions and reducing exposure risks.
How similar studies have performed: Previous work has found resistant Enterobacterales in animals and the environment, but directly linking those sources to human community infections remains largely unproven.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Logan, Latania K. — Emory University
- Study coordinator: Logan, Latania K.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.