When to deliver a baby with gastroschisis
Gastroschisis Outcomes of Delivery (GOOD) Study
This project compares outcomes of delivering babies with gastroschisis earlier versus closer to full term to help parents and doctors choose the best timing.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical College of Wisconsin NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project ID | NIH-11323048 on NIH RePORTER |
What this research studies
We will follow pregnant people whose fetus has been diagnosed with gastroschisis through the remainder of pregnancy, delivery, and the newborn period. The team will collect prenatal ultrasound findings, amniotic fluid and fetal growth measures, details about timing and mode of delivery, and newborn outcomes such as intestinal injury, surgeries, and NICU course. Researchers will compare results for babies delivered earlier versus those delivered nearer to term to identify which timing is linked to better health for babies. The work is led at the Medical College of Wisconsin and will include data from participating hospitals to inform clearer delivery timing guidance.
Who could benefit from this research
Good fit: Pregnant people with a prenatal diagnosis of fetal gastroschisis, particularly in the third trimester, are the ideal candidates for participation.
Not a fit: People without gastroschisis or those whose delivery timing is fixed by urgent maternal or unrelated fetal issues are unlikely to benefit directly from this project.
Why it matters
Potential benefit: If successful, this work could provide clearer guidance on delivery timing to reduce intestinal injury and avoid unnecessary prematurity harms.
How similar studies have performed: Only a couple of small, single-center randomized trials exist and retrospective studies have shown mixed results, so larger prospective data are still needed.
Where this research is happening
Milwaukee, United States
- Medical College of Wisconsin — Milwaukee, United States (Active)
Researchers
- Principal investigator: Wagner, Amy J — Medical College of Wisconsin
- Study coordinator: Wagner, Amy J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.