What drives stomach cancer and how it can be prevented in the US and worldwide
Comparative modeling of gastric cancer health drivers and prevention in the US and globally
Researchers are using computer models to compare causes and prevention approaches for stomach (gastric) cancer to help people at higher risk in the US and around the world.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11172417 on NIH RePORTER |
What this research studies
From a patient's view, the team combines existing medical records, population data, and results from prior studies to create computer simulations of stomach cancer risk and prevention. They compare approaches such as treating Helicobacter pylori infection and targeted endoscopic screening for people with early precursor changes. The models will estimate health outcomes, costs, and how strategies work in different groups and regions. The goal is to find which prevention and detection plans could save the most lives while using resources wisely.
Who could benefit from this research
Good fit: People most relevant to these findings are adults at higher risk for gastric cancer, such as those with H. pylori infection, certain ethnic groups with higher incidence, a family history, or precursor lesions like intestinal metaplasia.
Not a fit: People without known risk factors for gastric cancer or those seeking experimental drug treatments are unlikely to see direct benefit from this modeling project.
Why it matters
Potential benefit: This work could point to better, more targeted ways to prevent and detect stomach cancer, potentially reducing deaths and unnecessary procedures.
How similar studies have performed: Previous modeling and some clinical studies suggest H. pylori eradication and targeted surveillance can reduce gastric cancer, but how best to apply these approaches across U.S. populations is still being worked out.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Hur, Chin — Columbia University Health Sciences
- Study coordinator: Hur, Chin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.