NIH-funded research Sbir 1 grant

Wearable system to monitor alcohol withdrawal in real time

Official title: Wearable Sensor System for Continuous Monitoring of Alcohol Withdrawal Syndrome

Funded at Creare, LLC · NIH-11313084 · Data updated 2026-11-12

A wearable bracelet collects physiological data to continuously monitor alcohol withdrawal severity and help clinicians intervene early for adults with alcohol use disorder.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionCreare, LLC
NIH-funded
Lab location1 site (Hanover, United States)
Project startSeptember 1, 2026
Project endFebruary 28, 2027
Funding year2026
Award (this year)$314,357
NIH project number1R43AA032950-01
Project IDNIH-11313084 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 years and older with Alcohol Use Disorder who are at risk for alcohol withdrawal.

Less likely to help

People without AUD or who are not at risk for withdrawal may not benefit from this monitoring approach.

What this research studies

This project develops a real-time wearable sensor system that tracks tremor, heart rate, heart rate variability, sleep, and sweat ethanol to measure alcohol withdrawal severity. A machine learning model turns these signals into a continuous AWS severity score that aligns with standard clinical thresholds. The system is designed to work with the Ria Health telehealth platform to support remote clinician oversight in outpatient care. The goal is to provide objective, passive monitoring that complements or replaces infrequent in-person assessments, potentially reducing complications and hospitalizations. The work is in its early phase and will focus on translating physiological signals into actionable care in real-world settings.

Why it matters

Potential benefit: If successful, patients could receive timely interventions that prevent severe withdrawal and improve outpatient management.

How similar studies have gone: Previous efforts show that wearable sensors can detect withdrawal-related signals, but continuous real-time AWS monitoring in outpatient settings is still emerging.

Where this research is happening

  • Creare, LLC
    Hanover, United States
    Active

Researchers

  • Principal investigator: Archambault-Leger, Veronique — Creare, LLC
  • Study coordinator: Archambault-Leger, Veronique

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.