Wearable sensors and under-scalp EEG to forecast seizures and personalize treatment
Optimizing Pharmacotherapy with Noninvasive Wearable Sensors and Subscalp EEG
This project uses a wrist-worn sensor plus a small under-the-scalp EEG to forecast seizures for people with epilepsy so they can better time medications and reduce risks.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11064915 on NIH RePORTER |
What this research studies
You would wear a wrist device while also having a small, minimally invasive EEG sensor placed under the scalp for long-term monitoring. The team combines the continuous wearable signals and subscalp EEG recordings and uses computer algorithms to find patterns and cycles that predict times of higher seizure risk. Forecasts would be generated prospectively so you could get warnings or take short-acting medicine before a seizure starts. The goal is to make seizure risk more predictable without requiring deeply invasive brain implants.
Who could benefit from this research
Good fit: Ideal candidates are people with epilepsy who have recurrent seizures and are willing to have a subscalp EEG implanted and wear a wrist device for long-term monitoring.
Not a fit: People whose seizures are already fully controlled, who cannot or will not accept an implanted sensor, or who have extremely rare unpredictable seizures are less likely to benefit.
Why it matters
Potential benefit: If successful, this could give people advance warning of seizures so they can avoid dangerous activities and use fast-acting treatments to prevent or lessen seizures.
How similar studies have performed: Previous studies have shown seizure forecasting with implanted intracranial EEG and early reports with subscalp devices and wearables are promising, but broader US trials and FDA clearance remain limited.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Brinkmann, Benjamin H — Mayo Clinic Rochester
- Study coordinator: Brinkmann, Benjamin H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.