Wearable sensor platform to monitor Huntington's disease motor symptoms remotely
Official title: A Wearable Sensor Platform for Remote Monitoring of Motor Impairment in Huntingtons Disease and Prodromal Huntingtons Disease
Funded at Biosensics, LLC · NIH-11406110 · Data updated 2026-11-12
A wearable device called HDWear is being developed to continuously track movement and activity in people with Huntington's disease and those at risk, helping doctors understand motor impairment outside clinic visits.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Biosensics, LLC NIH-funded |
| Lab location | 1 site (Newton, UNITED STATES) |
| Project start | September 1, 2025 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $965,844 |
| NIH project number | 5R44TR005381-02 |
| Project ID | NIH-11406110 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with Huntington's disease, prodromal HD individuals, and age-matched controls who can wear and use the sensor.
✕Less likely to help
Patients who cannot wear a device or have conditions preventing reliable data collection may not benefit.
What this research studies
This project uses a wearable sensor to continuously monitor chorea and physical activity in people with Huntington's disease and prodromal individuals over a year. The team has already enrolled participants at a medical center and collected long-term data to validate how well HDWear reflects motor changes. By capturing real-world movement, the approach aims to provide more sensitive and timely insight into disease progression than clinic-based scales. The goal is to support future treatments by offering a reliable, patient-friendly way to track motor impairment. If successful, HDWear could become a practical tool for routine monitoring in HD care.
Why it matters
Potential benefit: If successful, patients could receive more accurate and timely monitoring of motor symptoms through everyday wear, potentially guiding treatment decisions and improving quality of life.
How similar studies have gone: Wearable sensors have shown promise in motor monitoring, but this project represents one of the longest continuous HD-specific wearable monitoring efforts.
Where this research is happening
-
Biosensics, LLC
Newton, United States Active
Researchers
- Principal investigator: Vaziri, Ashkan — Biosensics, LLC
- Study coordinator: Vaziri, Ashkan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.