Wearable patch that tracks blood chemicals and vital signs after injury

Metabolic and hemodynamic sensor for monitoring throughout the continuum of care

NIH-funded research University of California-Irvine · NIH-11325076

A thin wearable patch will continuously track blood oxygen, heart rate, lactate, glucose, and pH for people who have trauma, shock, or sepsis.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine NIH-funded
Lab location1 site (Irvine, United States)
Project IDNIH-11325076 on NIH RePORTER

What this research studies

I would wear a thin, flexible patch that holds a tiny sensor placed just under the skin. It continuously measures blood oxygenation, heart rate, lactate, tissue oxygen, glucose, and pH and sends the data wirelessly. The team will build the minimally invasive multi-analyte sensor first and then combine it with a wearable patch that adds pulse oximetry, autonomous operation, and wireless telemetry. The device is meant to provide real-time feedback during care and could be used for triage or to guide treatment decisions.

Who could benefit from this research

Good fit: Ideal candidates are people who have suffered trauma, are in shock, or are suspected to have sepsis and who can wear a small, minimally invasive sensor patch.

Not a fit: People without acute injury or infection, or those who cannot tolerate or wear a patch, are unlikely to benefit directly from this device.

Why it matters

Potential benefit: If successful, this could give earlier warning of worsening shock or sepsis and help clinicians direct faster, more targeted treatment.

How similar studies have performed: Prior work shows continuous vital-sign and lactate monitoring can predict outcomes, but combining multiple blood analytes in a thin under-skin wearable patch is relatively novel.

Where this research is happening

Irvine, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.