Water-based exercise and brain training for Veterans with mild memory loss

Water-based Activity to Enhance Recall in Veterans: A Randomized Clinical Trial

NIH-funded research Veterans Admin Palo Alto Health Care Sys · NIH-11361886

This project pairs water-based exercise with memory training to help Veterans aged 50–90 who have mild cognitive impairment (early memory problems).

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVeterans Admin Palo Alto Health Care Sys NIH-funded
Lab location1 site (Palo Alto, United States)
Project IDNIH-11361886 on NIH RePORTER

What this research studies

If you join, you will be randomly placed into either a six-month program that combines individualized, thrice-weekly pool exercise sessions with structured cognitive exercises or into a usual-care group, with about 190 Veterans enrolled. The exercise portion is water-based and delivered in group sessions while the cognitive training focuses on memory and thinking skills. Researchers will test thinking abilities, measure peak oxygen consumption, and check whether any gains last over time. The trial is single-blind and will also look at factors that might help predict who benefits most.

Who could benefit from this research

Good fit: Ideal candidates are Veterans aged 50–90 with a diagnosis of mild cognitive impairment who can safely participate in regular pool-based exercise.

Not a fit: People without MCI, those who cannot safely use a pool, or those with medical limitations that prevent regular exercise are unlikely to benefit from this trial.

Why it matters

Potential benefit: If successful, this program could improve memory and thinking and boost fitness for Veterans with mild cognitive impairment.

How similar studies have performed: Prior research shows that aerobic exercise and cognitive training can help thinking skills, but combining water-based exercise with cognitive training in Veterans with MCI is a newer approach that needs direct testing.

Where this research is happening

Palo Alto, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.