Wastewater testing for COVID-19 and other viruses on a Northern Plains tribal reservation

Strengthening COVID-19 prevention strategies via wastewater surveillance in a Northern Plains Tribe

NIH-funded research Black Hills Ctr/american Indian Health · NIH-11176969

This project will set up wastewater testing in 15 communities on a Northern Plains Lakota reservation to detect SARS-CoV-2 and other viruses earlier to help the local community.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBlack Hills Ctr/american Indian Health NIH-funded
Lab location1 site (Rapid City, United States)
Project IDNIH-11176969 on NIH RePORTER

What this research studies

If you live on the reservation, this program would collect wastewater from 15 communities to look for viral material like SARS-CoV-2, using laboratory sequencing to identify viral strains. The team will work closely with Tribal leaders and local health services to design and run the sampling in ways the community approves. Wastewater results will be coordinated with the reservation’s existing COVID-19 surveillance to give a community-level picture of viral activity. Researchers will also interview Tribal stakeholders and members to understand attitudes about wastewater testing and how it could be used locally.

Who could benefit from this research

Good fit: Ideal participants are residents, household members, local health staff, and Tribal stakeholders in the 15 communities of the Cheyenne River Sioux Tribe reservation who are part of community surveillance or interview activities.

Not a fit: People outside the covered reservation or individuals seeking personal diagnostic test results will not receive direct clinical diagnoses from wastewater surveillance.

Why it matters

Potential benefit: If successful, the program could give earlier, community-wide warning of viral outbreaks so local health leaders can target prevention and resources faster.

How similar studies have performed: Wastewater surveillance has successfully detected SARS-CoV-2 in many cities and campus settings, though applying sequencing-based wastewater testing in very remote Tribal reservations is less common.

Where this research is happening

Rapid City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.