Washington University Undiagnosed Diseases Diagnostic Center
Washington University in St. Louis UDN Diagnostic Center of Excellence
This program expands access to Washington University's Undiagnosed Diseases Network to help children and adults with unexplained conditions get diagnostic testing and coordinated follow-up.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11158830 on NIH RePORTER |
What this research studies
At Washington University, teams of clinicians, geneticists, and laboratory scientists work together to review patient histories, perform genomic testing, and run specialized laboratory studies to look for rare or previously unrecognized conditions. The center accepts referrals from patients and clinicians and uses a formal clinical and genomic review process to prioritize testing and research follow-up. Results can include a genetic diagnosis, new management recommendations, or enrollment in further research that uses model systems to understand disease. The program builds on the Undiagnosed Diseases Network and aims to make these services available to a broader group of patients through coordinated care and follow-up.
Who could benefit from this research
Good fit: Best suited for children and adults who have persistent unexplained symptoms or suspected genetic conditions that remain undiagnosed after standard clinical testing.
Not a fit: People with common, well-characterized conditions that already have an established diagnosis or who cannot travel or participate in follow-up are unlikely to benefit.
Why it matters
Potential benefit: If successful, the center could provide diagnoses, inform medical care, and connect families to resources or research for rare unexplained conditions.
How similar studies have performed: The Undiagnosed Diseases Network has a track record of diagnosing rare conditions and this center extends that proven model.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Dickson, Patricia I — Washington University
- Study coordinator: Dickson, Patricia I
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.