Washington University center creating comprehensive genetic and molecular profiles
Washington University Omics Production Center
['FUNDING_U01'] · WASHINGTON UNIVERSITY · NIH-11194253
This project will create detailed genetic and molecular data from people of diverse ancestries to help researchers understand disease better.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11194253 on ClinicalTrials.gov |
What this research studies
From a patient's view, the team will work with other sites to plan how volunteers are recruited and which biospecimens (like blood) are collected. They will run many lab tests on those samples, including whole genome sequencing, DNA methylation (bisulfite) sequencing, ATAC-seq for chromatin accessibility, RNA-seq, proteomics, and metabolomics. The center will use standardized workflows and quality checks, harmonize and integrate data across sites, and share the resulting multi-omics datasets with the research community. In the first year they will finalize protocols and after that they will begin large-scale data generation and sharing.
Who could benefit from this research
Good fit: Ideal candidates are people from ancestrally diverse backgrounds who are willing to provide biospecimens and health information for research.
Not a fit: People seeking immediate medical treatment or direct clinical benefit from joining are unlikely to receive direct personal health improvements from participation.
Why it matters
Potential benefit: If successful, the work could help researchers identify new disease markers and biological mechanisms, especially in underrepresented ancestral groups.
How similar studies have performed: Other large multi-omics and population projects (for example GTEx and All of Us) have successfully produced valuable datasets, though this effort focuses on improving representation across ancestries.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PATTI, GARY J — WASHINGTON UNIVERSITY
- Study coordinator: PATTI, GARY J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.