Wake Forest Atrium HeartShare Program for Heart Failure with Preserved Ejection Fraction

Wake Forest Atrium HeartShare Clinical Center

NIH-funded research Wake Forest University Health Sciences · NIH-11143222

This program at Wake Forest Atrium is gathering information from many people with a specific type of heart failure to better understand the condition.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences NIH-funded
Lab location1 site (Winston-Salem, United States)
Project IDNIH-11143222 on NIH RePORTER

What this research studies

Heart failure with preserved ejection fraction (HFpEF) is a common and serious condition where the heart struggles to pump blood effectively, but current treatments are limited because we don't fully understand it. This program, called HeartShare, is building a large group of patients with HFpEF and healthy volunteers to gather detailed information about their health. By collecting comprehensive data, researchers hope to uncover new ways this heart condition develops, identify different types of HFpEF, and find new targets for future treatments. Wake Forest Atrium is a leading center in this national effort, bringing extensive experience in working with diverse patient populations.

Who could benefit from this research

Good fit: Ideal candidates include individuals diagnosed with heart failure with preserved ejection fraction, as well as healthy volunteers willing to contribute to understanding this condition.

Not a fit: Patients without heart failure with preserved ejection fraction or those not serving as healthy controls may not directly benefit from participation in this specific program.

Why it matters

Potential benefit: If successful, this program could lead to the discovery of new ways to treat heart failure with preserved ejection fraction, offering hope for better patient outcomes.

How similar studies have performed: This program represents a coordinated, large-scale effort to address the current lack of understanding and effective treatments for HFpEF, building upon previous research that has not yet yielded significant breakthroughs.

Where this research is happening

Winston-Salem, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.