NIH-funded research R01 grant

Voice features as signs of movement issues in depression

Official title: Motoric features of the voice as indicators of psychomotor agitation and retardation in current and remitted MDD

Funded at Northwestern University at Chicago · NIH-11062507 · Data updated 2026-11-12

This study is looking at how certain sounds in your voice can show signs of restlessness or slowed movement in people with depression, and it lets you use your smartphone to record your speech so we can better understand your condition and help you feel better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startApril 1, 2024
Project endMarch 31, 2029
Funding year2025
Award (this year)$627,975
NIH project number5R01MH134369-02
Project IDNIH-11062507 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with major depressive disorder, particularly those experiencing psychomotor agitation or retardation.

Less likely to help

Patients who do not have major depressive disorder or those with stable, non-agitated forms of depression may not benefit from this research.

What this research studies

This research investigates how specific features of the voice can indicate psychomotor agitation and retardation in individuals with major depressive disorder (MDD). By analyzing vocal characteristics during natural speech, the study aims to identify objective markers of these psychomotor disturbances, which are often overlooked in traditional assessments. Participants will use their smartphones to record their speech, allowing for real-time monitoring and assessment of their condition. This innovative approach seeks to enhance understanding of MDD and improve treatment outcomes.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and objective assessments of depression, ultimately improving treatment strategies for patients.

How similar studies have gone: Previous research has shown promise in using vocal features as indicators of psychological conditions, suggesting that this approach may yield valuable insights.

Where this research is happening

  • Northwestern University at Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Shankman, Stewart Aaron — Northwestern University at Chicago
  • Study coordinator: Shankman, Stewart Aaron

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.