Voice features as signs of movement issues in depression

Motoric features of the voice as indicators of psychomotor agitation and retardation in current and remitted MDD

NIH-funded research Northwestern University at Chicago · NIH-11062507

This study is looking at how certain sounds in your voice can show signs of restlessness or slowed movement in people with depression, and it lets you use your smartphone to record your speech so we can better understand your condition and help you feel better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11062507 on NIH RePORTER

What this research studies

This research investigates how specific features of the voice can indicate psychomotor agitation and retardation in individuals with major depressive disorder (MDD). By analyzing vocal characteristics during natural speech, the study aims to identify objective markers of these psychomotor disturbances, which are often overlooked in traditional assessments. Participants will use their smartphones to record their speech, allowing for real-time monitoring and assessment of their condition. This innovative approach seeks to enhance understanding of MDD and improve treatment outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with major depressive disorder, particularly those experiencing psychomotor agitation or retardation.

Not a fit: Patients who do not have major depressive disorder or those with stable, non-agitated forms of depression may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and objective assessments of depression, ultimately improving treatment strategies for patients.

How similar studies have performed: Previous research has shown promise in using vocal features as indicators of psychological conditions, suggesting that this approach may yield valuable insights.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.