Virtual reality program to reduce chronic low back pain

Efficacy of a Virtual Reality Neuroscience-based Therapy for Chronic Low Back Pain

NIH-funded research Cognifisense, INC. · NIH-11322088

This project will see if a virtual-reality, brain-targeting treatment can reduce long-term low back pain in adults.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionCognifisense, INC. NIH-funded
Lab location1 site (Sunnyvale, United States)
Project IDNIH-11322088 on NIH RePORTER

What this research studies

You would use a patented VR program designed to target brain processes that keep pain going, with guided sessions delivered through a headset. The trial is a Phase II randomized controlled study comparing the VR treatment to a control approach to measure changes in pain and function. The team plans to enroll adults with chronic low back pain and follow them over time to measure lasting effects. Results from this trial are intended to support wider availability and possible FDA submission.

Who could benefit from this research

Good fit: Ideal candidates are adults aged 21 and older with chronic low back pain who are willing to participate in a randomized treatment program and follow study visits.

Not a fit: People with only acute or short-term back pain, those under 21, or patients with medical conditions that prevent VR use may not benefit from this trial.

Why it matters

Potential benefit: If successful, the VR approach could provide lasting, non-drug pain relief and reduce reliance on medications for chronic low back pain.

How similar studies have performed: A prior Phase I study by the same developer reported positive results, but larger randomized trials are still limited.

Where this research is happening

Sunnyvale, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.