NIH-funded research R01 grant

Vestibular implant to improve thinking, navigation, and balance after inner-ear damage

Official title: Vestibular implant tested in patients with peripheral vestibular damage: effects on spatial orientation, navigation, and neuropsychologic function

Funded at Massachusetts Eye and Ear Infirmary · NIH-11371741 · Data updated 2026-11-12

A vestibular implant is being offered to people with severe inner-ear balance damage to help improve thinking, spatial orientation, and navigation.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts Eye and Ear Infirmary
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 1, 2024
Project endJuly 31, 2029
Funding year2025
Award (this year)$112,008
NIH project number3R01DC021981-02S1
Project IDNIH-11371741 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults with severe, often bilateral, peripheral vestibular damage who experience balance-related cognitive problems and are eligible for implant surgery.

Less likely to help

People with only mild vestibular impairment, cognitive problems from non-vestibular causes, or who cannot undergo surgery may not benefit from this approach.

What this research studies

If you join, doctors will implant a device that senses your head’s motion in three dimensions and delivers long-term stimulation to the balance nerves. You will take part in tests of spatial orientation, navigation, memory, and other thinking skills while the team tracks how stimulation affects those abilities. The researchers will also follow people with varying degrees of vestibular loss who do not get the implant to compare outcomes. The goal is to see whether prosthetic vestibular signals can reduce cognitive problems caused by severe peripheral vestibular damage and to better understand how balance input supports thinking.

Why it matters

Potential benefit: If successful, the implant could improve memory, spatial navigation, and daily function for people with severe vestibular loss.

How similar studies have gone: Prior vestibular implant and prosthesis work has improved eye movements, balance, and gait, but using implants specifically to improve cognition is relatively new.

Where this research is happening

  • Massachusetts Eye and Ear Infirmary
    Boston, United States
    Active

Researchers

  • Principal investigator: Lewis, Richard F — Massachusetts Eye and Ear Infirmary
  • Study coordinator: Lewis, Richard F

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.