Vanderbilt center using live models to understand metabolism in obesity and diabetes
Vanderbilt Center for Metabolic Phenotyping in Live Models of Obesity and Diabetes
This center uses live mouse models to improve tools and methods that help scientists understand metabolic problems behind obesity and diabetes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project ID | NIH-11319720 on NIH RePORTER |
What this research studies
I would not join this work as a patient because it focuses on experiments in awake, unstressed mice, but the center supports research aimed at human obesity and diabetes. It runs three cores that provide administration and data management, animal health and welfare oversight, and a mouse metabolic physiology core that offers surgeries and controlled-environment experiments. External researchers can send animals or collaborate to use platforms that measure insulin action, hormone secretion, body-weight regulation, and other metabolic functions. The center standardizes and shares detailed physiological data to make preclinical research more reliable and comparable.
Who could benefit from this research
Good fit: This grant does not enroll patients; it supports laboratory research that may benefit people with obesity or diabetes in the future.
Not a fit: People seeking to join a clinical trial or those with conditions unrelated to metabolism are unlikely to receive any direct benefit from this center's activities.
Why it matters
Potential benefit: If successful, the center could speed development of better diabetes and obesity treatments by giving researchers more reliable metabolic data from live models.
How similar studies have performed: Vanderbilt's prior mouse metabolic phenotyping programs and similar centers have a multi-decade track record of enabling discoveries in diabetes and obesity.
Where this research is happening
Nashville, UNITED STATES
- Vanderbilt University — Nashville, United States (Active)
Researchers
- Principal investigator: Ayala, Julio E — Vanderbilt University
- Study coordinator: Ayala, Julio E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.