Validating human tissue for understanding neurodegenerative diseases
Core C: Human Tissue Validation
This study, led by Dr. Lea T. Grinberg, is looking at human tissue samples to learn more about neurodegenerative diseases, like tauopathies, and to help improve research tools for better understanding these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10906044 on NIH RePORTER |
What this research studies
This research focuses on the validation of human tissue samples to better understand the pathology and genetics of neurodegenerative diseases. Led by Dr. Lea T. Grinberg, the project aims to support ongoing research by providing well-characterized human tissue from patients with tauopathies and healthy controls. The team will also work on validating findings from related projects using these human specimens and developing new tools to enhance the information obtained from each sample.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with tauopathies or related neurodegenerative disorders.
Not a fit: Patients with neurodegenerative diseases not related to tauopathies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for neurodegenerative diseases.
How similar studies have performed: Previous research has shown success in using human postmortem tissue to advance understanding of neurodegenerative diseases, indicating this approach is promising.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Grinberg, Lea Tenenholz — Icahn School of Medicine at Mount Sinai
- Study coordinator: Grinberg, Lea Tenenholz
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.