Validating blood and imaging tests for brain health in diverse populations
Validation of Imaging and Blood-based Small Vessel VCID Biomarkers in Multiethnic Population
This study is looking for ways to use blood tests and eye scans to help understand how small blood vessel problems might affect thinking and memory, and it's open to people from different backgrounds in Los Angeles to make sure the results can help everyone.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-10907427 on NIH RePORTER |
What this research studies
This research focuses on validating various blood and imaging biomarkers that may indicate small vessel contributions to cognitive impairment and dementia. The study involves a multiethnic cohort, particularly from the diverse population in Los Angeles, to ensure that findings are applicable across different racial and ethnic groups. Participants will undergo noninvasive imaging of retinal capillaries and provide blood samples for analysis, contributing to a better understanding of how vascular health affects cognitive function. The goal is to establish reliable biomarkers that can be used in clinical settings to identify at-risk individuals.
Who could benefit from this research
Good fit: Ideal candidates include individuals from multiethnic backgrounds, particularly those at risk for cognitive impairment or dementia.
Not a fit: Patients who do not have any risk factors for cognitive impairment or dementia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection and management of cognitive impairment and dementia in diverse populations.
How similar studies have performed: Previous research has shown promise in using similar biomarkers for cognitive impairment, indicating potential for success in this approach.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Wang, Danny Jj — University of Southern California
- Study coordinator: Wang, Danny Jj
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.