Validating biomarkers for cognitive impairment related to small vessel disease
MarkVCID Validation in the General Community
This study is looking for 200 people who are at risk for memory problems related to small blood vessel issues in the brain, to help find better ways to spot and understand how these issues affect thinking and memory.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10619433 on NIH RePORTER |
What this research studies
This research aims to identify and validate biomarkers associated with cerebral small vessel disease (SVD), which is linked to cognitive impairment and dementia. The study will recruit a diverse group of 200 participants at risk for vascular contributions to cognitive impairment and dementia (VCID) from multiple sites, including Mayo Clinic Rochester and University of Mississippi Medical Center. Using a two-step screening approach, the research will leverage existing clinical and imaging data from a large longitudinal study to enhance participant recruitment and evaluation. The goal is to improve understanding and detection of SVD's impact on cognitive health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for vascular contributions to cognitive impairment and dementia, particularly those from diverse backgrounds.
Not a fit: Patients who do not have risk factors for cognitive impairment or small vessel disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools for identifying individuals at risk of cognitive decline due to small vessel disease.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for cognitive impairment, suggesting that this approach could yield valuable insights.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Petersen, Ronald C — Mayo Clinic Rochester
- Study coordinator: Petersen, Ronald C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.