UW SIREN network to improve emergency care for brain, heart, lung, blood injuries and severe trauma
University of Washington HUB Network for Emergency Care Clinical Trials: Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN)
Building and running a network that helps hospitals and EMS offer clinical trials to people with life‑threatening brain, heart, lung, or blood emergencies and severe trauma.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11307588 on NIH RePORTER |
What this research studies
This project renews a coordinated network based at the University of Washington and Harborview that links hospitals, King County EMS, and partner sites including the University of British Columbia to support emergency care clinical trials. The Hub will provide administrative, academic, and regulatory oversight while local hospitals and EMS act as enrolling sites or spokes. The grant funds the infrastructure and coordination for pragmatic trials but does not itself open or approve specific clinical trials. A central IRB (previously established) continues to handle trial approvals for studies run through the network.
Who could benefit from this research
Good fit: Ideal candidates would be people who experience life‑threatening emergency conditions (brain, heart, lung, blood) or severe trauma and are treated at participating hospitals or by partner EMS services.
Not a fit: Patients with routine or non‑emergency conditions, or those treated outside the network's hospitals and EMS regions, would not be part of these trials and likely would not benefit directly from this grant.
Why it matters
Potential benefit: If successful, the network could speed up high‑quality emergency care studies and bring new, proven treatments to patients faster across the Pacific Northwest.
How similar studies have performed: This renewal builds on the existing SIREN network that has previously supported pragmatic emergency care trials, so the approach is established though each individual trial will be new.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Kudenchuk, Peter James — University of Washington
- Study coordinator: Kudenchuk, Peter James
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.