Using zonisamide to help treat alcohol use disorder
Zonisamide for the Treatment of Alcohol Use Disorder in the Addiction Neuroclinical Assessment Framework
This study is looking at how well the medication zonisamide can help people with alcohol use disorder by tracking their drinking habits and sticking to their treatment, while also offering rewards for cutting back on alcohol.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington State University NIH-funded |
| Lab location | 1 site (Pullman, United States) |
| Project ID | NIH-10912622 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of zonisamide, an anticonvulsant medication, in treating alcohol use disorder (AUD). The study aims to improve treatment outcomes by incorporating objective measures of alcohol consumption and medication adherence, which have been lacking in previous trials. Participants will receive incentives for verified reductions in alcohol use, creating a structured support system. The research is grounded in the Addiction Neuroclinical Assessment framework, focusing on key psychological factors that influence addiction.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are diagnosed with alcohol use disorder.
Not a fit: Patients who are not diagnosed with alcohol use disorder or those who are not willing to participate in a structured treatment program may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new and effective treatment option for individuals struggling with alcohol use disorder.
How similar studies have performed: Previous studies have shown promise for zonisamide in treating alcohol use disorder, but this research aims to address limitations found in earlier trials.
Where this research is happening
Pullman, United States
- Washington State University — Pullman, United States (Active)
Researchers
- Principal investigator: Mcpherson, Sterling M — Washington State University
- Study coordinator: Mcpherson, Sterling M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.