NIH-funded research R21 grant

Using yeast in soda to kill disease-carrying mosquitoes

Official title: Buy the world a coke and keep it mosquito free

Funded at Indiana University Indianapolis · NIH-11056405 · Data updated 2026-11-12

This study is testing a new, eco-friendly way to control disease-spreading mosquitoes by using a special soda bottle that attracts them with yeast and delivers a targeted insecticide, helping to keep our communities safe from illnesses like dengue and chikungunya.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionIndiana University Indianapolis
NIH-funded
Lab location1 site (Indianapolis, United States)
Project startJune 18, 2025
Project endMay 31, 2027
Funding year2025
Award (this year)$433,303
NIH project number1R21AI182680-01A1
Project IDNIH-11056405 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals living in areas heavily affected by mosquito-borne diseases.

Less likely to help

Patients living in regions where mosquito-borne diseases are not prevalent may not benefit from this research.

What this research studies

This research aims to develop a new method for controlling mosquito populations that spread diseases like dengue and chikungunya. By using eco-friendly RNA interference technology, the study will create a system where mosquitoes are attracted to a soda bottle containing yeast that delivers a targeted insecticide. This innovative approach seeks to lure mosquitoes away from natural sugar sources while minimizing harm to other species. The project will test the effectiveness of this method in real-world settings to combat insecticide resistance.

Why it matters

Potential benefit: If successful, this research could significantly reduce mosquito populations and the diseases they transmit, improving public health.

How similar studies have gone: Other research has shown promise in using RNA interference for pest control, but this specific approach with yeast and soda is novel.

Where this research is happening

  • Indiana University Indianapolis
    Indianapolis, United States
    Active

Researchers

  • Principal investigator: Scheel, Molly Duman — Indiana University Indianapolis
  • Study coordinator: Scheel, Molly Duman

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.