Using Xenon MRI to improve diagnosis of pulmonary hypertension
Xenon MRI in Pulmonary Hypertension
This study is looking at a special type of MRI that uses a gas called 129Xe to create detailed 3D images of the lungs, which could help doctors better diagnose and track pulmonary arterial hypertension (PAH) in patients, ultimately aiming to improve their treatment and health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10909083 on NIH RePORTER |
What this research studies
This research investigates the use of 129Xe magnetic resonance imaging (MRI) to create detailed 3D maps that can help diagnose and monitor pulmonary arterial hypertension (PAH). By focusing on the unique characteristics of PAH, this method aims to provide a noninvasive way to assess changes in the pulmonary blood-gas barrier and vascular remodeling. The goal is to improve treatment guidance and health outcomes for patients suffering from this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with pulmonary arterial hypertension who require ongoing monitoring and treatment.
Not a fit: Patients with other forms of pulmonary hypertension or those who do not have a diagnosis of pulmonary arterial hypertension may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and noninvasive methods for diagnosing and monitoring pulmonary hypertension, ultimately improving patient care.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for similar conditions, indicating potential for success with this novel approach.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Rajagopal, Sudarshan K — Duke University
- Study coordinator: Rajagopal, Sudarshan K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.