NIH-funded research NIH-funded research

Using xenon gas to help treat opioid withdrawal symptoms

Official title: Xenon gas inhalation as a novel treatment for opioid withdrawal syndrome

Funded at General Biophysics, LLC · NIH-11035534 · Data updated 2026-11-12

This study is looking at whether breathing in xenon gas can help people going through opioid withdrawal feel better by calming their symptoms, and it's designed for those struggling with opioid use.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionGeneral Biophysics, LLC
NIH-funded
Lab location1 site (Wayland, United States)
Project startFebruary 1, 2025
Project endJanuary 31, 2026
Funding year2025
Award (this year)$400,000
NIH project number1R41DA061962-01
Project IDNIH-11035534 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults over 21 years old who are experiencing opioid withdrawal symptoms.

Less likely to help

Patients who are not experiencing opioid withdrawal or those who are not opioid-dependent may not benefit from this research.

What this research studies

This research investigates the use of xenon gas inhalation as a potential treatment for opioid withdrawal syndrome (OWS). The approach focuses on how xenon can inhibit the sympathetic nervous system activity that drives the distressing symptoms of withdrawal. By partnering with established hospitals, the study aims to develop a safe and effective inhaled treatment that could ease the transition for individuals with opioid use disorder. The research will involve administering xenon gas in controlled settings to assess its impact on withdrawal symptoms.

Why it matters

Potential benefit: If successful, this research could provide a novel and effective treatment option for individuals experiencing opioid withdrawal, potentially reducing the risk of relapse and overdose.

How similar studies have gone: Previous research has shown promise in using xenon gas for similar applications, indicating potential for success in this novel approach.

Where this research is happening

  • General Biophysics, LLC
    Wayland, United States
    Active

Researchers

  • Principal investigator: Ilin, Ilya — General Biophysics, LLC
  • Study coordinator: Ilin, Ilya

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.