Using xenon gas to help treat opioid withdrawal symptoms

Xenon gas inhalation as a novel treatment for opioid withdrawal syndrome

NIH-funded research General Biophysics, LLC · NIH-11035534

This study is looking at whether breathing in xenon gas can help people going through opioid withdrawal feel better by calming their symptoms, and it's designed for those struggling with opioid use.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionGeneral Biophysics, LLC NIH-funded
Lab location1 site (Wayland, United States)
Project IDNIH-11035534 on NIH RePORTER

What this research studies

This research investigates the use of xenon gas inhalation as a potential treatment for opioid withdrawal syndrome (OWS). The approach focuses on how xenon can inhibit the sympathetic nervous system activity that drives the distressing symptoms of withdrawal. By partnering with established hospitals, the study aims to develop a safe and effective inhaled treatment that could ease the transition for individuals with opioid use disorder. The research will involve administering xenon gas in controlled settings to assess its impact on withdrawal symptoms.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who are experiencing opioid withdrawal symptoms.

Not a fit: Patients who are not experiencing opioid withdrawal or those who are not opioid-dependent may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a novel and effective treatment option for individuals experiencing opioid withdrawal, potentially reducing the risk of relapse and overdose.

How similar studies have performed: Previous research has shown promise in using xenon gas for similar applications, indicating potential for success in this novel approach.

Where this research is happening

Wayland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injuryAlzheimer's disease model
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.